NIH Patents and Patent Applications

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Lead IC Reference Number Title Country Patent Application Type Application Number Date Filed Patent Number Date Issued Patent Status Patent PDF
NIAID E-131-2015-2-US-52 NEUTRALIZING ANTIBODIES TO GP120 AND THEIR USE US REISSUE 19/038,583 Pending
NICHD E-004-2024-0-PC-01 Enhanced Tumor Reactivity of T cells lacking SIT1, LAX1 or TRAT1 PCT PCT PCT/US2025/013054 Pending
NCI E-237-2017-2-KR-01 T CELL RECEPTORS RECOGNIZING MUTATED P53 KR DIV 10-2025-7002917 Pending
NIAID E-197-2023-1-KR-01 ANTI-SARS-CoV-2 ANTIGEN BINDING POLYPEPTIDES, POLYPEPTIDE COMPLEXES AND METHODS OF USE THEREOF [COM5] KR National Stage 10-2025-7002965 Pending
NIAID E-197-2023-0-KR-01 ANTI-SARS-COV-2 ANTIGEN BINDING POLYPEPTIDES, POLYPEPTIDE COMPLEXES AND METHODS OF USE THEREOF KR National Stage 10-2025-7002966 Pending
NIAID E-197-2023-1-AU-01 ANTI-SARS-CoV-2 ANTIGEN BINDING POLYPEPTIDES, POLYPEPTIDE COMPLEXES AND METHODS OF USE THEREOF AU National Stage 2023301087 Pending
NIAID E-131-2015-2-US-53 NEUTRALIZING ANTIBODIES TO GP120 AND THEIR USE US CON 19/035,336 12545719 Issued PDF
NCI E-068-2018-0-HK-01 TETHERED INTERLEUKIN-15 AND INTERLEUKIN-21 HK CN 42025102573.0 Pending
NIBIB E-139-2022-2-CN-01 METHODS AND COMPOSITIONS FOR IMPROVING WOUND HEALING CN National Stage 202380055558.7 Abandoned
NCATS E-035-2020-1-US-04 TREATING PRIMARY OR IDIOPATHIC HYPEROXALURIA WITH SMALL MOLECULE INHIBITORS OF LACTATE DEHYDROGENASE US CON 19/032,915 Pending
NLM E-111-2022-2-CN-01 ECHOCARDIOGRAPHIC ESTIMATION OF RIGHT ATRIAL PRESSURE USING A LIGHTWEIGHT AND OPEN-WORLD ARTIFICIAL INTELLIGENCE SYSTEM CN National Stage 202380055216.5 Abandoned
NLM E-107-2010-2-US-44 SELECTIVE OXIDATION OF 5-METHYLCYTOSINE BY TET -FAMILY PROTEINS US CON 19/028,618 12467082 Issued PDF
NIAID E-064-2016-1-US-11 PREFUSION RSV F PROTEINS AND THEIR USE US CON 19/031,097 Pending
NIAID E-260-2014-0-US-08 RECOMBINANT METAPNEUMOVIRUS F PROTEINS AND THEIR USE US CON 19/029,797 Pending
NICHD E-228-2024-0-US-01 Carboxypeptidase E mimic small molecules for neuroprotection and neurodegenerative disease treatment US 63/746,513 Expired
NCI E-181-2019-0-CN-02 Chimeric Antigen Receptors Containing Glypican 2 Binding Domains CN DIV 202510075685.4 Pending
NCI E-044-2022-0-JP-01 KINASE INHIBITORS JP National Stage 2025-502384 Pending
NCI E-044-2022-0-US-02 KINASE INHIBITORS US National Stage 18/995,318 Pending
NIAID E-045-2015-0-EP-13 Neutralizing Antibodies to Ebola Virus Glycoprotein and Their Use EP DIV 25152319.7 Abandoned
NCI E-183-2017-0-KR-01 ANTI-B-CELL MATURATION ANTIGEN CHIMERIC ANTIGEN RECEPTORS WITH HUMAN DOMAINS KR DIV 10-2025-7001390 Pending
NHLBI E-134-2022-0-IL-01 SYSTEMS AND METHODS FOR ELECTROCARDIOGRAPHIC RADIAL DEPTH
NAVIGATION OF INTRACARDIAC DEVICES 		IL National Stage 318413 Abandoned
NCI E-129-2022-0-EP-01 CD25-SPECIFIC ANTIBODIES AND USES THEREOF EP National Stage 23745029.1 Pending
NIAAA E-110-2022-0-EP-01 METABOTROPIC GLUTAMATE RECEPTOR 5 ANTAGONISTS COMPOSITIONS AND METHODS FOR THE TREATMENT OF FIBROSING PULMONARY DISEASES EP National Stage 23739715.3 Pending
NIAID E-177-2022-0-EP-01 MONOCLONAL ANTIBODIES THAT BIND TO THE UNDERSIDE OF INFLUENZA VIRAL NEURAMINIDASE EP National Stage 23761340.1 Pending
NIAID E-157-2022-0-US-02 COMPOSITIONS AND METHODS FOR TREATMENT OF VIRUS-INDUCED AIRWAY FIBROSIS US National Stage 18/993,347 Pending
NCI E-239-2017-0-JP-02 HLA CLASS I-RESTRICTED T CELL RECEPTORS AGAINST MUTATED RAS JP DIV 2025-003895 Pending
NCI E-129-2022-0-IN-01 CD25-SPECIFIC ANTIBODIES AND USES THEREOF IN National Stage 202517002483 Pending
NIAID E-025-2026-0-US-01 Antigen Binding Polypeptides, Polypeptide Complexes and Methods of Use Thereof in HIV US 63/891,829 Expired
NIBIB E-139-2022-2-US-01 METHODS AND COMPOSITIONS FOR IMPROVING WOUND HEALING US National Stage 18/992,393 Pending
NIBIB E-139-2022-2-EP-01 METHODS AND COMPOSITIONS FOR IMPROVING WOUND HEALING EP National Stage 23750873.4 Pending
NIAID E-197-2023-1-EP-01 ANTI-SARS-COV-2 ANTIGEN BINDING POLYPEPTIDES, POLYPEPTIDE COMPLEXES AND METHODS OF USE THEREOF EP National Stage 23832655.7 Pending
NIBIB E-139-2022-2-JP-01 METHODS AND COMPOSITIONS FOR IMPROVING WOUND HEALING JP National Stage 2025-500850 Abandoned
NLM E-111-2022-2-KR-01 ECHOCARDIOGRAPHIC ESTIMATION OF RIGHT ATRIAL PRESSURE USING A LIGHTWEIGHT AND OPEN-WORLD ARTIFICIAL INTELLIGENCE SYSTEM KR National Stage 10-2025-7000599 Abandoned
NCI E-147-2024-1-US-01 BETA-CATENIN INHIBITORS AND DEGRADERS US 63/742,947 Abandoned
NIDCD E-173-2022-0-US-02 IMPEDING PLATINUM-BASED CHEMOTHERAPEUTIC INDUCED OTOTOXICITY USING A COLONY STIMULATING FACTOR 1 RECEPTOR INHIBITOR US National Stage 18/881,825 Pending
NIAID E-197-2023-0-EP-01 ANTI-SARS-COV-2 ANTIGEN BINDING POLYPEPTIDES, POLYPEPTIDE COMPLEXES AND METHODS OF USE THEREOF EP National Stage 23832656.5 Pending
NCI E-186-2022-0-EP-01 PREDICTING PATIENT RESPONSE TO CANCER THERAPY VIA HISTOPATHOLOGY IMAGES EP National Stage 23820358.2 Pending
NHLBI E-100-2022-0-JP-01 VERY-LONG-CHAIN POLYUNSATURATED FATTY ACIDS (VLCPUFA) FOR IMPROVING RETINA/COGNITIVE FUNCTIONS AND ATHEROSCLEROSIS JP National Stage 2025-500370 Pending
NICHD E-115-2022-0-JP-01 PROGESTIN / TESTOSTERONE TRANSDERMAL GEL JP National Stage 2024-566565 Pending
NHLBI E-100-2022-0-US-02 VERY-LONG-CHAIN POLYUNSATURATED FATTY ACIDS (VLCPUFA) FOR IMPROVING RETINA/COGNITIVE FUNCTIONS AND ATHEROSCLEROSIS US National Stage 18/881,578 Pending
NCATS E-006-2022-0-EP-01 LATS INHIBITORS AND USES THEREOF EP National Stage 23736525.9 Pending
NCI E-076-2022-0-US-02 CELL-BARCODE RECORDER DEVICES AND METHODS US National Stage 18/881,523 Pending
NIAID E-086-2023-0-PC-01 NOVEL COMPOSITIONS OF MATTER COMPRISING PROTEINS THAT INCORPORATE PFS230 DOMAIN 1 (PFS230D1) AT THE N-TERMINUS, MALARIA VACCINE ANTIGENS, AND THEIR USE PCT PCT PCT/US2025/010325 Pending
CC E-056-2022-0-PCT-01 EMBOLIC MICROSPHERES PCT PCT PCT/US2025/010283 Pending
NCI E-118-2024-0-EP-01 AUGMENTING MITOCHONDRIA IN IMMUNE CELLS FOR IMPROVED CANCER IMMUNOTHERAPY EP National Stage 23738432.6 Pending
NHLBI E-036-2015-1-US-01 NK CELLS WITH AN INCREASED ANTIBODY-DEPENDENT CELLULAR TOXICITY (ADCC) AGAINST TUMORS US DIV 19/008,042 Pending
NHLBI E-057-2024-0-PC-01 Use of LMO4 to bolster stemness and antitumor efficacy of T-cells PCT PCT PCT/EP2025/050005 Pending
NIAAA E-110-2022-0-CN-01 METABOTROPIC GLUTAMATE RECEPTOR 5 ANTAGONISTS COMPOSITIONS AND METHODS FOR THE TREATMENT OF FIBROSING PULMONARY DISEASES CN National Stage 202380051444.5 Abandoned
NHLBI E-264-2023-0-US-01 CAR WITH DUAL-VARIABLE DOMAIN AND ENHANCED TCR-SIGNALING TARGETING CT-RCC-1 PEPTIDE AND METHODS OF USE US 63/740,485 Expired
NHLBI E-264-2023-1-US-01 CAR WITH DUAL-VARIABLE-DOMAIN AND ENHANCED TCR-SIGNALING (CADET) AND
METHODS OF USE 		US 63/740,496 Expired