NIH Patents and Patent Applications

This list includes non-provisional and PCT patent filings.

Download a CSV of all Patent records.

For information on patent application codes, country codes, and patent status, see the Patents FAQ.

Tips:
Reset Search to show all records.
Sort columns by clicking on the blue column headers.
The Search function searches across all columns.
To filter results by Lead IC, Country, or Application, type or use the dropdown menu.

Lead IC Reference Number Title Country Patent Application Type Application Number Date Filed Patent Number Date Issued Patent Status Patent PDF
NCI E-020-2024-0-PC-01 CHIMERIC ANTIGEN RECEPTORS TARGETING FGFR4 AND/OR CD276 AND USE THEREOF FOR THE TREATMENT OF CANCER PCT PCT PCT/US2025/024757 Pending
NIAID E-004-2009-2-US-30 VIRUS LIKE PARTICLE COMPOSITIONS AND METHODS OF USE US CON 19/179,890 Pending
NCI E-155-2024-0-PC-01 MULTIFUNCTIONAL MOLECULES BINDING TO TCR AND USES THEREOF PCT PCT PCT/US2025/024019 Pending
NIDDK E-059-2024-0-PC-01 MODIFIED PIGGYBAT TRANSPOSITION SYSTEM AND USES THEREOF PCT PCT PCT/US2025/024004 Pending
NIA E-030-2024-0-PC-01 ACCELERATION OF MULTIDIMENSIONAL MAGNETIC RESONANCE IMAGING (MRI)
ACQUISITION VIA K-SPACE PARTIAL SAMPLING AND PARTIAL RECONSTRUCTION 		PCT PCT PCT/US2025/023881 Pending
NIBIB E-054-2018-0-HK-01 CHEMICAL CONJUGATES OF EVANS BLUE DERIVATIVES AND THEIR USE AS RADIOTHERAPY AND IMAGING AGENTS FOR TARGETING PROSTATE CANCER HK CN 2024108723712 Pending
NCI E-181-2017-0-AU-01 HLA CLASS II-RESTRICTED T CELL RECEPTORS AGAINST MUTATED RAS AU DIV 2025202532 Pending
NIAID E-174-2023-0-CA-01 Self-Assembling Nanoparticles CA National Stage 3270145 Pending
NIAID E-174-2023-0-ZA-01 Self-Assembling Nanoparticles ZA National Stage 2025/02016 Pending
NIAID E-174-2023-0-JP-01 Self-Assembling Nanoparticles JP National Stage 2025-523964 Pending
NIA E-092-2011-0-US-02 USE OF (2R, 6R)-HYDROXYNORKETAMINE, (S)-DEHYDRONORKETAMINE AND OTHER STEREOISOMERIC DEHYDRO AND HYDROXYLATED METABOLITES OF (R,S)-KETAMINE IN THE TREATMENT OF DEPRESSION AND NEUROPATHIC PAIN US CON 19/172,611 Pending
NIA E-090-2024-0-PC-01 S-HYDROXYCHLOROQUINE, OPTIONALLY WITH TAUROURSODEOXYCHOLIC ACID AND/OR 3,3′-DIINDOLYLMETHANE, FOR TREATING AND/OR PREVENTING NEUROLOGICAL DISORDERS PCT PCT PCT/US2025/023133 Pending
NCI E-045-2024-0-PC-01 POTENT FGFR4-TARGETED ANTIBODY-DRUG CONJUGATES AND THEIR USE FOR TREATING CANCERS EXPRESSING FGFR4 PCT PCT PCT/US2025/023122 Pending
NIAID E-197-2023-2-PC-01 ANTIGEN BINDING POLYPEPTIDES, POLYPEPTIDE COMPLEXES AND METHODS OF USE THEREOF PCT PCT PCT/US2025/023073 Pending
NIAID E-197-2023-2-US-02 Antigen Binding Polypeptides, Polypeptide Complexes and Methods of Use Thereof US ORD 19/170,000 Pending
NIDA E-208-2022-0-EP-01 Dopamine D3/D2 Receptor Partial Agonists For The Treatment Of Neuropsychiatric Disorders EP National Stage 23800603.5 Pending
NEI E-070-2019-0-JP-08 INTERLEUKIN-27 PRODUCING B-CELL POPULATION AND USES THEREOF JP DIV 2025-061994 Pending
NCATS E-001-2023-1-US-02 MULTI-CYCLC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF US National Stage 19/118,179 Pending
NCI E-206-2022-0-US-02 T CELL RECEPTORS TARGETING MUTATED CDKN2A US National Stage 19/118,202 Pending
NCI E-213-2022-0-US-02 HLA-A3-RESTRICTED T CELL RECEPTORS AGAINST BRAF WITH V600E MUTATION US National Stage 19/118,121 Pending
NCI E-027-2024-0-PC-01 METHODS OF DETECTING LOSS OF HETEROZYGOSITY AND DAMAGING MUTATIONS IN
IMMUNE-RELATED GENES IN LIQUID BIOPSIES 		PCT PCT PCT/US2025/022568 Pending
NCI E-101-2024-0-PC-01 METHODS TO IDENTIFY AND SELECTIVELY EXPAND TUMOR ANTIGEN-SPECIFIC T CELLS PCT PCT PCT/US2025/022247 Pending
NEI E-058-2018-0-JP-01 USING MACHINE LEARNING AND/OR NEURAL NETWORKS TO VALIDATE STEM CELLS AND THEIR DERIVATIVES FOR USE IN CELL THERAPY, DRUG DISCOVERY, AND DIAGNOSTICS JP DIV 2025-055757 Pending
NIDA E-208-2022-0-US-02 DOPAMINE D3/D2 RECEPTOR PARTIAL AGONISTS FOR THE TREATMENT OF NEUROPSYCHIATRIC DISORDERS US National Stage 19/116,951 Pending
NCI E-087-2024-0-PC-01 RADIOLABELED GLYPICAN-3 (GPC3)-SPECIFIC SINGLE DOMAIN ANTIBODY AND USE THEREOF AS AN IMAGING AGENT FOR DETECTION OF GPC3-POSITIVE TUMORS PCT PCT PCT/US2025/021789 Pending
NEI E-015-2019-0-US-02 BIODEGRADABLE TISSUE REPLACEMENT IMPLANT AND ITS USE US CON 19/092,324 Pending
NIAID E-183-2022-0-EP-01 NANOPARTICLE-DERIVED VACCINES AGAINST POXVIRUSES, AND METHODS FOR MAKING AND USING THE SAME EP National Stage 23776760.3 Pending
NCI E-017-2023-0-US-02 Directed Acetylation of mRNA Through Engineered snoRNA Adapters US National Stage 19/116,059 Pending
NHLBI E-223-2022-0-US-02 PHYSIOLOGICAL NAVIGATION IN MRI USING INHERENT SLAB-SELECTIVE FREE-INDUCTION-DECAY SIGNAL US National Stage 19/115,948 Pending
NIBIB E-076-2020-0-US-03 FLUORESCENCE SCANNING SYSTEM FOR ANALYTICAL ULTRACENTRIFUGATION US CON 19/088,688 Abandoned
CC E-242-2023-0-PCT-01 SYSTEMS AND METHODS FOR AN AUGMENTED REALITY GUIDANCE SYSTEM PCT PCT PCT/US2025/020993 Pending
NEI E-089-2011-0-US-05 CONJUGATES FOR TREATING INFLAMMATORY DISEASE AND IDENTIFICATION OF PATIENTS LIKELY TO BENEFIT FROM SUCH TREATMENT US CON 19/086,582 Pending
NIDA E-208-2022-0-CA-01 Dopamine D3/D2 Receptor Partial Agonists For The Treatment Of Neuropsychiatric Disorders CA National Stage 3268476 Pending
NCI E-135-2019-0-TW-01 T CELL RECEPTORS RECOGNIZING R175H OR Y220C MUTATION IN P53 TW DIV 114110844 Pending
NIAID E-240-2023-0-KR-01 VACCINES AGAINST CORONAVIRUSES KR National Stage 10-2025-7009272 Pending
NCI E-167-2017-0-KR-01 NOVEL CANCER TREATMENT UTILIZING PRE-EXISTING MICROBIAL IMMUNITY KR DIV 10-2025-7009189 Pending
NIDA E-208-2022-0-AU-01 Dopamine D3/D2 Receptor Partial Agonists For The Treatment Of Neuropsychiatric Disorders AU National Stage 2023353560 Pending
NIAID E-117-2024-0-PC-01 RESPIRATORY SYNCYTIAL VIRUS (RSV) G AND F ANTIBODIES WITH HIGH RSV-NEUTRALIZING POTENCY PCT PCT PCT/US2025/020070 Pending
NHLBI E-134-2022-0-EP-01 SYSTEMS AND METHODS FOR ELECTROCARDIOGRAPHIC RADIAL DEPTH NAVIGATION OF INTRACARDIAC DEVICES EP National Stage 23765412.4 Pending
NCI E-002-2018-0-US-02 METHODS OF PRODUCING T CELL POPULATIONS USING P38 MAPK INHIBITORS US CON 19/079,743 Abandoned
NCI E-076-2024-0-PC-01 T CELL RECEPTORS TARGETING E545K OR N345K MUTATION IN PIK3CA PCT PCT PCT/US2025/019733 Pending
NCI E-167-2017-0-JP-02 NOVEL CANCER TREATMENT UTILIZING PRE-EXISTING MICROBIAL IMMUNITY JP DIV 2025-039507 Pending
NCI E-230-2020-0-US-02 Recurrence Gene Signature Across Multiple Cancer Types US DIV 19/077,957 Pending
NIAID E-140-2022-0-EP-01 Dual-Germline Antibody Engager HIV-1 Envelope Chimeric Immunogens EP National Stage 23765112.0 Pending
NIAID E-174-2023-0-AU-01 Self-Assembling Nanoparticles AU National Stage 2023367780 Pending
NHLBI E-052-2022-0-HK-01 INFUSION DEVICE FOR THE PREPARATION AND DELIVERY OF MRI PROBES HK CN 62025104551.9 Abandoned
NIAID E-174-2023-0-IL-01 Self-Assembling Nanoparticles IL National Stage 320235 Pending
NIDDK E-003-2024-0-PC-01 POLYPEPTIDE CONSTRUCTS WITH POTENT ANTI-HIV ACTIVITY PCT PCT PCT/US2025/019228 Pending
NCI E-175-2016-0-JP-02 ANTI-KRAS-G12D T CELL RECEPTORS JP DIV 2025-036871 Pending
NIAID E-119-2025-0-US-02 Compositions of Bifunctional Inhibitors of Tetracycline Inactivating Enzymes and Methods of Use Thereof US ORD 19/072,517 Pending