Product Showcase

The HHS Intramural Research Programs have invented numerous technologies that were licensed to companies for commercial development and now are on the market. Products showcased on this site are utilized every day to detect, treat or prevent disease or assist researchers as they continue to explore ways to develop newer and more effective health care products and procedures.

The Showcase includes products that are now or have been on the market. Some are FDA-approved and many do not necessitate FDA approval. While there may be multiple inventors on any product, all of whom may not be from HHS, the primary purpose of this Showcase is to highlight the contributions of HHS. 

We hope you will find this Showcase illuminating about the role the HHS Intramural Research Programs have played in the effort to advance significantly our capacity to protect and improve health.

Sigma Chemical Corporation

Research tool/reagent for nonhuman investigations

Sigma Chemical Corporation

Employed in various DNA repair mechanism studies

Bausch and Lomb

Nutritional supplement to treat macular degeneration

Cytogen Corporation

Serves as a antibody based radiolabeling agent that detects colorectal and ovarian cancer

PanVera LLC

Used for Cytochrome p450 inhibition and phenotyping

University of Leiden (Sub-licensed: Biotrin International)

Detection of B19 virus IgM antibodies in human serum and plasma

Abbott Molecular Inc.

Prognosis of breast cancer (in conjunction with other clinical data)

Ventana Medical Systems, Inc.

Assessment of breast cancer patients for whom Herceptin� treatment is considered.

Aros Biotech AB

HIV research tool

Santa Cruz Biotechnology, Inc.

Recommended for detection of PDGFR-α of human origin by IF and FCM

Bachem Holding AG

Used as a building block for the synthesis of cell-permeable protein tyrosine phospatase (PTP) inhibitors

Arcturus Engineering, Inc.

Laser Capture Microdissection (LCM) is used for microdissection of single cells or small number of cells

BD Biosciences - BD PharMingen

Reacts with platelet derived growth factor (PDGF) receptor α

Intracel Corporation

Detects mature and precursor proteases

Taconic Farm, Inc.

Mouse model used to study biochemical mechanism involved in cholesterol lowering drugs.

Janssen Therapeutics

Treatment of HIV-1 infection.

Tibotec Pharmaceuticals, Ltd.

Treatment of patients with HIV-1 strains resistant to more than one protease inhibitor

NeoMarkers, Inc.

Detects and binds to prolactin receptors

Sanyo Chemical Industries, Ltd.

Used to coat a wide variety of cell culture containers and materials due to its unique ability to promote cell attachment

TriLink BioTechnologies, Inc.

Due to exquisite sensitivity to changes in the environment, they can be used for the study of DNA interactions.

OraSure Technologies, Inc.

Screens for the presence of antibodies to HIV-1 and HIV-2.

Immunetics, Inc.

Screens for the presence of antibodies to HIV-1 and HIV-2.

R&D Systems, Inc.

Designed for the quantitative determination of activated human TGF-b1 concentrations in cell culture supernatant, serum, plasma, and urine

Oncogene Sciences, Inc.

Use for the quantitation of circulating ras p21 in human serum and plasma

Veritas, Inc.

Used for designing HIV protease inhibitors, which serves as an important component of combination therapies for HIV

Intracel Corporation

Used for ELISA and western blot studies.

R&D Systems, Inc.

IL­2 plays a central role in the expansion and  maintenance of regulatory T cells

Techne Corporation

sFRPs contain cysteine-rich domain Wnt ligands in Frizzleds that provides a novel, secreted protein that contains a region homogulous to ligand binding domain of a cytokine receptor.

Bristol-Myers Squibb Company

Used to target the Lewis-Y antigen for therapeutic and diagnostic purposes

Merial Limited

Vaccine for dogs against distemper, parvovirus, hepatitis, respiratory disease and parainfluenza virus.