Product Showcase

The HHS Intramural Research Programs have invented numerous technologies that were licensed to companies for commercial development and now are on the market. Products showcased on this site are utilized every day to detect, treat or prevent disease or assist researchers as they continue to explore ways to develop newer and more effective health care products and procedures.

The Showcase includes products that are now or have been on the market. Some are FDA-approved and many do not necessitate FDA approval. While there may be multiple inventors on any product, all of whom may not be from HHS, the primary purpose of this Showcase is to highlight the contributions of HHS. 

We hope you will find this Showcase illuminating about the role the HHS Intramural Research Programs have played in the effort to advance significantly our capacity to protect and improve health.

L-205-2001

K1 antibodies

Zymed Laboratories, Inc.

Used as a research reagent to enhance the understanding of certain cancers, such as, ovarian, esophageal and cervical carcinomas
L-049-1991

Kepivance®

Amgen, Inc.

Treatment of severe mouth sores that afflict hematologic cancer patients who receive myelotoxic therapy
L-266-2000

Keratinocyte Growth Factor & KGF Antibodies

PeproTech, Inc.

Identifies keratinocyte of growth factors, i.e. embryonic development, cell growth, morphogenesis, tumor growth,and invasion
L-163-1997

LambdaSelect-cII™ Mutation Assay Kit

Stratagene California

Detect in vivo mutations of E. coli phage lambda 1
L-183-1997

Long Terminal Repeat Vector

Stratagene California

Uses LTR vectors to screen for a protein of interest.
L-041-1997

LTR-Vectors

Novartis Pharma, Genetic Therapy, Inc.

Used to make retroviral vectors for development of gene therapy products
Luxturna vial

Luxturna®

Spark Therapeutics

Treatment of inherited vision loss due to specific gene mutations.
L-006-1985

LYMErix™

GlaxoSmithKline

A noninfectious recombinant vaccine for Lyme's disease
L-088-1997

Macrophage Stimulating Protein

Research and Diagnostic Systems, Inc.

Activates macrophages to react in the immune system
L-002-2004

MART-1 Antibody

Cell Marque Corporation

Diagnostic assay for metastatic melanoma
L-038-1987

Matrigel®

Becton Dickinson

Substrate for culturing cells
L-024-1997

Melanoma-associated antigen recognized by T cells (MART-1) Antibodies

Signet Laboratories, Inc.

This antibody is very useful in establishing the diagnosis of metastatic melanomas
L-242-2002

Melanoma-associated antigen recognized by T cells (MART-1) Melan A

Biocare Medical, LLC

Labels melanomas and tumors showing melanocytic differentiation
L-138-2005

Mesothelin (K1)

Santa Cruz Biotechnology, Inc.

Used as a therapeutic for mesotheliomas and pancreatic and ovarian tumors
L-151-1995

Micro HTLV-1/2

Abbott Laboratories, Inc.

Uses multiple antigens to detect HTLV-1 and HLTV-2
L-222-1998

Microsomes, S9 Fractions and Cytosol

Invitrogen Corporation

Used for Cytochrome p450 inhibition and phenotyping
L-328-2000

Monoclonal Antibodies to HIV-1

Intracel Corporation

Identify and trace specific cells or molecules in an organism
L-005-1991

Monoclonal antibody

Signet Laboratories, Inc.

Markers used for identifying breast cancer cells
L-049-1994

Monoclonal antibody J52 and C3

Affinity BioReagents, Inc.

Identify and trace specific cells or molecules in an organism
L-167-1996

Monoclonal Antibody to human CD82

BD Biosciences - BD PharMingen

Identify and trace specific cells or molecules in an organism
L-187-1995

Monocyte chemotactic protein-1 Antibodies

BD Biosciences - BD PharMingen

Antibody reacts with mouse/rat/human Monocyte chemotactic protein-1 and is used to detect Monocyte chemotactic protein-1
L-154-1997

Mouse anti-14-3-3 epsilon

BD Biosciences - BD PharMingen

Anti-14-3-3 ε recognizes the expressed product of the YWHAE gene, also known as Ywhae.
L-180-1996

Mouse Mammary Tumor Virus-bla HeLa Cell Line

Invitrogen Corporation

Allows for the analysis of endogenous glucocorticoid receptor signaling
L-078-1996

Murine D551 antibody

Upstate Biotechnology, Incorporated

Identify PLK enzymes in vitro
L-275-1996

Murine Stem Cell Virus Retroviral Expression System

Clontech Laboratories, Inc

Contains 3 vectors: pMSCVneo, pMSCVhyg, and pMSCVpuro that enhances research to be done with hard-to-transduce cell lines
L-183-1996

MutaPlax cII-Select Kit

Epicentre Technologies Corporation

Measures mutation frequencies of lambda-based in vivo mutagenesis systems using a new positive selection method.
Myalept packaging

Myalept®

Aegerion Pharmaceuticals

Treatment for leptin deficiency in congenital/acquired lipodystrophy
L-042-1993

NeoTect®

Berlex Laboratories, Inc.

Serves as an imaging agent for radiation scans of lung lesions in cancer patients and patients at high-risk for cancer
L-060-1990

NeuTrexin® (Trimetrexate)

MedImmune Oncology

Treatment for infections due to toxoplasma gondii and pneumocystis carinii in immunocompromised patients, including patients with AIDS
L-186-1994

Nitric Oxide Complexes with Polyamines

Dojindo Laboratories

Used for the treatment of cardiovascular disorders