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NIH inventors have developed the first known method of producing Regulatory B-cells (Bregs) ex-vivo. There is a great need to supplement the low population of Bregs in a patient suffering from an autoimmune disease where Breg levels are severely reduced, such as uveitis. This method involves

The technology is an exciting discovery in the field of prostate, breast and lung cancer genetic markers having profound clinical applications in defining the optimal chemotherapeutic treatment schedule for each individual patient. This genetic marker (CYP1B1*3) can potentially be used as a

As detailed in a recent press release, an international team led by researchers from the National Human Genome Research Institute (NHGRI) has identified a genetic variant that is a major contributor to small size in dogs. The findings appear in the April 6, 2007 issue of the journal Science. To

This technology identifies a new form of Cushing syndrome, "isolated micronodular adrenocortical disease" (iMAD), classified as a rare disease, as well as the role of PDE11A gene in this disease. Particular sequence variants of the PDE11A gene associated with abnormal or altered function of the gene