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    The NIH Office of Technology Transfer (OTT) plays a strategic role by supporting the patenting and licensing efforts of our NIH ICs. OTT protects, monitors, markets and manages the wide range of NIH discoveries, inventions, and other intellectual property as mandated by the Federal Technology Transfer Act and related legislation.

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TYROSINASE Gene Therapy for Oculocutaneous Albinism type 1A

  • Read more about TYROSINASE Gene Therapy for Oculocutaneous Albinism type 1A

Summary:

The National Eye Institute seeks research co-development partners and/or licensees for an adeno-associated viral gene therapy for Oculocutaneous Albinism type 1A.  

Novel Kinase Inhibitory Aplithianines

  • Read more about Novel Kinase Inhibitory Aplithianines

Summary:

The National Cancer Institute (NCI) seeks research co-development partners and/or licensees for a class of novel aplithianine-derived small molecule analogs that compete with ATP for binding on a range of clinically relevant kinases including:

Reverse Thiazine Kinase Inhibitors

  • Read more about Reverse Thiazine Kinase Inhibitors

Summary:

The National Cancer Institute (NCI) seeks research co-development partners and/or licensees for a class of novel aplithianine-derived small molecule analogs that compete with ATP for binding on a range of clinically relevant kinases including:

Novel Kinase Inhibitory Thiazines

  • Read more about Novel Kinase Inhibitory Thiazines

Summary:

The National Cancer Institute (NCI) seeks research co-development partners and/or licensees for a class of novel aplithianine-derived small molecule analogs that compete with ATP for binding on a range of clinically relevant kinases including:

AI Based Workflow for Single Cell Analysis

  • Read more about AI Based Workflow for Single Cell Analysis

The National Eye Institute (NEI) seeks research co-development partners and/or licensees for single-cell RNA sequencing (scRNA-seq) analysis software that leverages existing large language models (LLM) to simplify and enhance data analysis by providing intelligent recommendations and interpretations.

RPGR Gene Therapy for Retinitis Pigmentosa

  • Read more about RPGR Gene Therapy for Retinitis Pigmentosa

The National Eye Institute (NEI) seeks research co-development partners and/or licensees for the development of RPGR gene therapy for Retinitis Pigmentosa.

Targeted Disruption of Rpe65 Gene for Retinal Disease Research

  • Read more about Targeted Disruption of Rpe65 Gene for Retinal Disease Research

The National Eye Institute (NEI) seeks research co-development partners and/or licensees for the development of a targeted disruption of the Rpe65 gene in mice, a novel model for studying retinal diseases and testing potential therapies.

Innovative Gene Therapy for Retinal Diseases

  • Read more about Innovative Gene Therapy for Retinal Diseases

The National Eye Institute (NEI) seeks research co-development partners and/or licensees for the development of innovative gene therapy for retinal diseases.

Stable Cell Line for Large Scale Production of Human Retinoschisin for Ocular Therapy

  • Read more about Stable Cell Line for Large Scale Production of Human Retinoschisin for Ocular Therapy

The National Eye Institute (NEI) seeks research co-development partners and/or licensees for the development of a stable cell line for the production of human Retinoschisin (RS1) for therapeutic applications in ocular diseases.

Gene Therapy for Leber Congenital Amaurosis

  • Read more about Gene Therapy for Leber Congenital Amaurosis

The National Eye Institute (NEI) seeks research co-development partners and/or licensees for the development of an AAV gene therapy for Leber Congenital Amaurosis caused by CEP290 mutations.

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Office of Technology Transfer, Office of Intramural Research, National Institutes of Health