New, First-in-class Immunotherapy for Treatment of Recurrent, Metastatic Cervical Cancer

In 2011, NCI and Iovance Biotherapeutics entered into a CRADA for the development of Adoptive Cell Therapy (ACT) using Tumor Infiltrating Lymphocytes (TIL). Technology licenses between NCI and Iovance were established to grant Iovance rights to the NIH’s TIL patent estate. By 2019, Iovance began conducting two pivotal multi-center trials of TIL technology in advanced cervical cancer and metastatic melanoma and has achieved Breakthrough Therapy and Fast Track designations from the FDA in these indications, respectively.

Lab to Market Training for Post-doctoral Scientists Across the NIH

In September 2016, to better engage and educate the scientific community, the NCI TTC launched the first federal Technology Transfer Ambassadors Program (TTAP). The program has significantly impacted TT efforts at the NCI and is now being offered across the NIH. TTAP is the first formal TT training and mentoring program open to NIH post-doctoral (post-docs) scientists and staff scientists/staff clinicians seeking professional development in invention analysis, commercialization, and entrepreneurship.

Annual National Cancer Institute and Frederick National Laboratory Technology Showcase

The National Cancer Institute’s (NCI) Technology Transfer Center (TTC) has taken home a State and Local Economic Development award from the 2021 Federal Laboratory Consortium (FLC) awards. The NCI TTC started a yearly event in 2017 with the Frederick National Laboratory (FNL) to highlight technologies and inventions available for licensing and collaboration. Hosting the event at FNL allowed everyone to take advantage of the regional resources and relationships that the City and County of Frederick have.