Technology ID
TAB-5116

Innovative Gene Therapy for Retinal Diseases

E-Numbers
E-070-2021-0
Lead Inventor
Gentleman, Susan
Lead IC
NEI
Co-Inventors
Redmond, Thomas
ICs
NEI
Applications
Therapeutics
Therapeutic Areas
Rare/Neglected Diseases
Ophthalmology
Development Stages
Prototype
Research Products
Virus/Bacteria
Plasmids/Vectors

The National Eye Institute (NEI) seeks research co-development partners and/or licensees for the development of innovative gene therapy for retinal diseases.

This technology includes an innovative gene therapy approach aimed at treating retinal diseases, which are a leading cause of vision loss. Retinal diseases, such as age-related macular degeneration and retinitis pigmentosa, affect millions of people worldwide and currently have limited treatment options. Our gene therapy targets the underlying genetic causes of these diseases, offering a potential cure rather than just symptomatic relief.

The technical solution involves the use of adeno-associated virus (AAV) vectors to deliver therapeutic genes directly to retinal cells. This method is significant because it not only addresses the root cause of the disease but also has the potential for long-lasting effects, reducing the need for frequent treatments. You should care about this technology because it represents a breakthrough in the field of ophthalmology, with the potential to restore vision and improve the quality of life for patients suffering from debilitating retinal conditions.

We are seeking licensing partners who are interested in co-developing this groundbreaking technology. The ideal partner would have experience in gene therapy and a commitment to advancing innovative treatments in ophthalmology. We are open to discussions regarding collaboration and are eager to explore opportunities that align with our goals for this technology.

Commercial Applications
• Treatment of age-related macular degeneration • Therapy for retinitis pigmentosa • Potential applications in other retinal disorders • Development of combination therapies with existing treatments

Competitive Advantages
• Targeted gene delivery using AAV vectors • Potential for long-lasting therapeutic effects • Addresses the root cause of retinal diseases • High safety profile with minimal side effects • Opportunity to significantly improve patient outcomes
Licensing Contact:
Pollard, Ricquita
ricquita.pollard@nih.gov