Technology ID
TAB-5080

Innovative Antibody Conjugation Technology for Therapeutic and Diagnostic Applications

E-Numbers
E-176-2025-0
Lead Inventor
Borris, Frank
Lead IC
NIBIB
Co-Inventors
Fathi, Parinaz
Sadtler, Kaitlyn
ICs
NIBIB
Applications
Therapeutics
Diagnostics
Therapeutic Areas
Oncology
Infectious Disease
Development Stages
Prototype

This pioneering technology introduces a novel method for conjugating antibodies, designed to dramatically enhance their therapeutic and diagnostic performance. By improving both binding efficiency and target specificity, this approach overcomes critical limitations of existing antibody-based therapies and imaging tools.

The result is a versatile platform that enables more effective treatments and more precise diagnostics, unlocking new possibilities in disease management. With particular impact in oncology, where accurate targeting is vital, and in infectious diseases, where rapid and reliable detection can save lives, this technology has the potential to redefine standards of care across multiple fields.

By uniting next-generation engineering with broad clinical applicability, this innovation represents a transformative step forward in antibody-based medicine—delivering greater accuracy, improved patient outcomes, and expanded opportunities for both therapy and diagnosis.

Commercial Applications
  • Therapeutic agents for targeted cancer treatment.
  • Diagnostic imaging agents for early disease detection.
  • Research tools for studying immune responses.
Competitive Advantages
  • Enhanced binding efficiency leading to improved therapeutic outcomes.
  • Versatile application across multiple therapeutic areas, including oncology and infectious diseases.
  • Potential for rapid commercialization due to established interest from pharmaceutical companies.
Licensing Contact:
Knezevic, Vladimir
vlado.knezevic@nih.gov