Technology ID
TAB-5077

Innovative Antibody Conjugates for Targeted Therapy

E-Numbers
E-118-2022-0
Lead Inventor
Rezvan Sangsari, Paniz
Lead IC
NIBIB
Co-Inventors
Morgan, Nicole
Fathi, Parinaz
Sadtler, Kaitlyn
ICs
NIBIB
Applications
Therapeutics
Diagnostics
Therapeutic Areas
Oncology
Immunology
Development Stages
Discovery

This advanced technology introduces innovative antibody conjugates that redefine the possibilities of targeted therapy. By coupling therapeutic agents to engineered antibodies with highly specific binding sites, these conjugates deliver treatments directly to diseased cells while sparing healthy tissues. The result is a powerful increase in treatment efficacy, accompanied by a meaningful reduction in side effects.

Designed with cutting-edge engineering techniques, the platform offers exceptional versatility, enabling adaptation across a wide range of therapeutic areas. Its greatest potential lies in oncology, where precision targeting is critical for destroying tumor cells while preserving patient health, and in immunology, where carefully modulating immune responses can transform chronic disease management.

By uniting precision targeting, enhanced safety, and broad therapeutic applicability, this technology represents a major step forward in the evolution of targeted therapies, offering new hope for improved patient outcomes and more effective treatments.

Commercial Applications
  • Targeted cancer therapies using engineered immune cells.
  • Diagnostic imaging agents for precise disease detection.
  • Therapeutic agents for autoimmune diseases.
Competitive Advantages
  • High specificity and reduced off-target effects, leading to improved patient safety.
  • Versatile applications across multiple therapeutic areas, including oncology and immunology.
  • Potential for rapid development and commercialization due to established engineering techniques.
Licensing Contact:
Knezevic, Vladimir
vlado.knezevic@nih.gov