Technology ID
TAB-4613
Real-time RT-PCR Assay for Rapid, Highly Sensitive and Specific Detection of Human Enterovirus D68 (EV-D68
E-Numbers
E-011-2015-1
Lead Inventor
Nix, William
Lead IC
CDC
ICs
CDC
Applications
Medical Devices
Diagnostics
Therapeutic Areas
Pulmonology
Infectious Disease
Development Stages
Pre-Clinical (in vitro)
Research Products
Plasmids/Vectors
This technology includes a real-time RT-PCR (reverse transcriptase – polymerase chain reaction) Taqman assay using primers and probes specific for EV-D68 viral protein 1 nucleic acid. This assay provides a more specific identification of EV-D68 strains allowing better diagnosis. Human Enterovirus D68 (EV-D68) is a non-polio enterovirus that can cause mild to severe respiratory illness, especially in infants and children with asthma. The assay is simple, validated, and allows rapid testing and detection of EV-D68 in respiratory samples. This assay can be used in a kit or an array format for high-throughput (large scale) screening of samples, which is useful for public health facilities and surveillance programs.
Commercial Applications
Rapid, simple and specific detection of new human EV-D68 strains for research or clinical settings to diagnose respiratory infections directly attributable to EV-D68 versus other causative agents.
Competitive Advantages
- Detection of currently circulating, newly evolved human EV- D68 strains
- Simple and rapid as compared to previous methods, making the diagnosis easier
- High sensitivity and specificity
- Validated and easily implementable as a kit or array for high-throughput sample screening
- Faster screening than culturing and serological identification methods
- This assay was approved under an Emergency Use Authorization (EUA) by the FDA in May, 2015
Licensing Contact: