Technology ID

Affinity Purified Polyclonal Antibody Against Vangl2 (Van Gogh-like) as a Research Tool Product

Lead Inventor
Montcouquiol, Mireille (INSERM)
Research Materials
Development Stages
Pre-Clinical (in vitro)
Research Products
Lead IC

This technology includes an antibody that enables the identification and isolation of the protein and protein partners of Vangl2 for application by western blotting, immunoprecipitation and immunocytochemistry. Because planar cell polarity signaling disruption leads to direct or indirect pathologies including malformation of the neural tube, mental retardation, disruption of sensory functions (hearing, balance, vision), cancers (polykystic kidneys disease), or cardiac

malformations and disruption of chirality (situs inversus), we can envision that the antibody could be used as a diagnostic tool.

Commercial Applications
Vialed and sold as a diagnostic research product, furthering the work of researchers focused on Planar Cell Polarity, including Vangl2, by enabling access to a valuable reagent tool.

Competitive Advantages
Enables access to a valuable reagent tool.
Licensing Contact:
Shmilovich, Michael