Technology ID
              TAB-4543
          Endo-cameral Closure Device for Structural Heart Defects and Blood Vessel Repair
E-Numbers
          E-273-2015-0
              Lead Inventor
          Rogers, Toby
              Lead IC
          NHLBI
              Co-Inventors
          Kocaturk, Ozgur
          Lederman, Robert
          Sonmez, Merdim
              ICs
          NHLBI
              Applications
          Research Materials
          Medical Devices
              Therapeutic Areas
          Cardiology
              Development Stages
          Pre-clinical (in vivo)
              Research Products
          Research Equipment
              This technology includes a device to close a hole in the wall of a large blood vessel or cardiac chamber from the inside out, delivered over a guidewire and through a catheter or sheath. First, the proximal portion deploys within the vessel or chamber and is advanced over a guidewire to oppose the wall and seal the hole. Second, the distal portion self-assembles outside the vessel or chamber upon withdrawal of the guidewire. Deployment of the distal portion anchors the device securely in place.
Commercial Applications
              This device could become a critical tool to have available in every interventional catheterization laboratory.
      Competitive Advantages
              There are currently no commercially available devices to close holes in the wall of large blood vessels or cardiac chambers, and has the potential to enable novel procedures that are not possible currently because of a lack of custom closure device.
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