Technology ID

Expanded Claims for Transcatheter Coronary Sinus Mitral Valve Annuloplasty Procedure and Coronary Artery and Myocardial Protection

Lead Inventor
Lederman, Robert (NHLBI)
Medical Devices
Therapeutic Areas
Development Stages
Pre-clinical (in vivo)
Lead IC

This technology includes a novel transcatheter repair for functional mitral valve regurgitation, called mitral cerclage annuloplasty. This includes coronary artery protection for mitral cerclage annuloplasty against inside-out compression from subsequent transcatheter valve-in-ring mitral valve implantation, wherein the ring is created by the cerclage annuloplasty. Cerclage annuloplasty is to create a semi-rigid ring at the level of the mitral annulus. The purpose of this ring is to create a “landing zone” for a percutaneous mitral valve implant, which guides positioning of the percutaneous transcatheter mitral valve and also allows the valve to use outward compression against the cerclage annuloplasty for fixation. The value in this invention is that the arch not only protects the artery against compression from the outer surface of the annuloplasty but it also protects against compression from the heart surface of the coronary artery ‘inside-out”, when a transcatheter aortic valve is implanted in relation to or in tandem with the cerclage annuloplasty.

Commercial Applications
To be used to repair functional mitral valve regurgitation.

Competitive Advantages
At present there is heavy market interest in transcatheter mitral valve implantation.
Licensing Contact:
Mistry, Pragnesh