Technology ID

Antibody to Mitochondrial Uniporter (MCU

Lead Inventor
Finkel, Toren (NHLBI)
Pan, Xin (NHLBI)
Research Materials
Development Stages
Pre-Clinical (in vitro)
Research Products
Lead IC

This technology includes a generated polyclonal antibody in rabbit that detects the mitochondrial uniporter (MCU) protein. This antibody was created by immunizing rabbits with a synthesized sequence of the MCU protein and can be used to identify and quantify MCU protein in various tissues. The polyclonal nature of the antibody ensures it recognizes multiple epitopes on the MCU, enhancing detection reliability. This technology is crucial for understanding MCU's role in mitochondrial function and mammalian physiology.

Commercial Applications
The rabbit polyclonal antibody against the mitochondrial calcium uniporter (MCU) can be applied in biomedical research to investigate mitochondrial dysfunctions in various diseases, in drug development targeting mitochondrial pathways, and in advancing our understanding of cellular bioenergetics and apoptosis.

Competitive Advantages
The rabbit polyclonal antibody's ability to target multiple epitopes on the mitochondrial calcium uniporter (MCU) offers a competitive advantage in reliably detecting and quantifying MCU protein, crucial for in-depth studies of its role in mitochondrial function and overall cell physiology.
Licensing Contact:
Shmilovich, Michael