Inglese, James (NHGRI)
Cheng, Chih-Chien (Ken) (NCATS)
Macarthur, Ryan (NCATS)
Guha, Rajarshi (NCATS)
Su, Xin-zhuan (NIAID)
Yuan, Jing (NIAID)
Ni, Feng (Boston University)
Beeler, Aaron (Boston University)
Schaus, Scott (Boston University)
Brown, Lauren (Boston University)
Porco, John (Boston University)
This technology includes three new compound classes displaying either differential or comprehensive antimalarial activity across geographically diverse lines. These compounds were identified from a quantitative high throughput screen of a novel chemical library with unique chemical complexity and are potential candidates for treating malaria.
Compounds display comprehensive antimalarial activity.