Suryanarayanan, Raj (University of Minnesota)
Gurvich, Vadim (University of Minnesota)
Sadhukha, Tanmoy (University of Minnesota)
Thakral, Seema (University of Minnesota)
This technology includes a stable pharmaceutical formulation of propofol hemisuccinate for inhalation delivery to treat intractable epilepsy and migraine. The formulation can be used to treat a patient experiencing a seizure aura to prevent a motor seizure. Alternatively, the formulation can be used to treat an epileptic patient who is experiencing seizure clusters in an out-of-hospital or in-hospital setting. For migraines, the formulation can be used to treat a patient experiencing a migraine aura or early migraine to forestall the development of the full symptoms of a migraine headache.
The current formulation is the first available treatment optimized for inhalation delivery for the treatment of both epilepsy and migraine.