Technology ID

Pre-Biotic Formulation of Topical Chemicals for Use on Human Skin

Lead Inventor
Myles, Ian (NIAID)
Castillo, Carlo (NIAID)
Lead IC
Atopic dermatitis (AD) is a common, recurrent, chronic inflammatory skin disease that is a cause of considerable economic and social burden. It is one of the most prevalent skin disorders, affecting ~25% of children in developed and developing countries and is expected to continue to escalate. This increased rate of incidence has changed the focus of research on AD toward epidemiology, prevention, and treatment.

Scientists at NIAID have developed novel topical formulations that promote the growth of health-associated strains of commensal bacteria and inhibit disease-associated bacteria, thereby enhancing skin health.

This technology is available for licensing for commercial development in accordance with 35 U.S.C. 209 and 37 CFR part 404, as well as for further development and evaluation under a research collaboration.
Commercial Applications
  • Over-the-counter formulations—this invention could be readily incorporated into popular body lotions or other skincare products to make “enhanced”/“microbiome-friendly” versions that promote the growth of health associated bacterial
Competitive Advantages
  • Benign safety profile with multiple mechanisms of action
  • Proven enhancement of beneficial microbiota
  • Can be readily incorporated into existing products
Licensing Contact:
Yang, David (Po-Lung)