Shirvan, Mitchell (Synerra Medical)
Gorodetsky, Rafael (Hadassah Medical Center)
Kuznetsov, Sergei (NIDCR)
Lazmi-Hailu, Astar (Hadassah Medical Center)
The subject technology discloses a tissue engineering method for treating cartilage damage. Stem cells from bone marrow are attached to a novel scaffold, hyaluronic acid-coated fibrin microbeads, and transferred to a live host to form cartilage. The regenerated cartilage is stable and not hypertrophic, which has been problematic in the current regenerative methods.
- A novel scaffold, hyaluronic acid-coated fibrin microbeads.
- Cartilage repair.
- Coating with hyaluronic acid makes the fibrin microbeads more stable for mature cartilage formation.
- The new hyaline cartilage is stable and hypertrophy-resistant.