Regulator of G Protein Signaling (RGS13) Knock-Out Mouse
Druey, Kirk (NIAID)
Xie, Zhi Hui (Sherry) (NIAID)
RGS13, an intracellular protein in mast cells, was shown to suppress IgE-mediated anaphylactic response in mice. The RGS13-/- mouse may be used to screen compounds that inhibit mast cell degranulation.