Technology ID
TAB-3202
Regulator of G Protein Signaling (RGS13) Knock-Out Mouse
E-Numbers
E-181-2008-0
Lead Inventor
Druey, Kirk
Lead IC
NIAID
Co-Inventors
Xie, Zhi Hui (Sherry)
ICs
NIAID
Applications
Research Materials
RGS13, an intracellular protein in mast cells, was shown to suppress IgE-mediated anaphylactic response in mice. The RGS13-/- mouse may be used to screen compounds that inhibit mast cell degranulation.
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