Technology ID

Field-Adapted Spot Test for Evaluating Materials Treated with Permethrin Insect Repellent

Lead Inventor
Green, Michael (CDC)
Research Materials
Consumer Products
Therapeutic Areas
Infectious Disease
Development Stages
Development Status
Lead IC
Military uniforms and mosquito nets are treated with permethrin, a repellent and insecticide used for personal protection against biting flies, mosquitoes, and other disease-carrying insects. Vector-borne diseases such as malaria, leishmaniasis (a parasitic infection spread by sandflies), Zika virus, West Nile virus, Lyme disease, and more can be diminished if treated nets or clothing containing the proper amount of permethrin are utilized. Washing and wear depletes the insecticide on the material, eventually rendering it ineffective. Currently, there are no commercially available colorimetric (color-changing) tests available to gauge the amount of permethrin left in fabrics after use and repeated washes. CDC researchers developed a rapid and simple technique using a reagent to quantify the amount of permethrin in the treated fabric. The low cost colorimetric spot test yields color intensity proportional to the permethrin concentration levels and has been adapted into a prototype for field testing. The technology provides a rapid means to evaluate permethrin-treated materials, such as military uniforms, outdoor gear, mosquito nets, and curtains.
Commercial Applications
  • Kits containing spot test for military personnel operating in the field
  • Kits can be available for use in programs aimed to reduce the spread of diseases caused by insect bites such as malaria or Lyme disease
  • Kits can be made available to frequent outdoorsmen/women (e.g., hikers, campers, and hunters) who use permethrin-treated clothing, tents, camping gear, etc.
Competitive Advantages
  • First to market potential – currently, there are no commercially-available colorimetric assays for permethrin although they are available for other synthetic pyrethroids (insecticides) such as deltamethrin
  • Low-cost kit is ideal for field use
  • Spot tests are rapid and easy to use
  • The kit can be adapted to provide an indication by color intensity of whether the material needs to be retreated or discarded
Licensing Contact:
Mitzelfelt, Jeremiah