Technology ID
TAB-2976
A Novel Rapid Point-of Care Diagnostic Method for Infectious and Autoimmune Diseases
E-Numbers
E-190-2015-0
Lead Inventor
Burbelo, Peter (NIDCR)
Applications
Non-Medical Devices
Medical Devices
Diagnostics
Therapeutic Areas
Infectious Disease
Immunology
Geriatrics
Endocrinology
Development Stages
Discovery
Development Status
- Early-stage
- In vitro data available
- Prototype
Research Products
Research Equipment
Antibodies
Lead IC
NIDCR
ICs
NIDCR
Rapid point-of-care, antibody-based testing is not available for the diagnosis of autoimmune and most infectious diseases. For detecting autoantibodies associated with most autoimmune conditions, fluid-phase immunoprecipitation assays are required. However, these assays usually involve radioactivity and are not feasible for point-of-care applications. The subject invention describes methods of using neodymium magnet for diagnosis of infectious and autoimmune diseases including lupus, Sjögren's syndrome, type I diabetes, HIV and Lyme disease. The assay takes 3.5 minutes, is highly efficient, and has low background.
Commercial Applications
- A rapid assay for point-of-care diagnosis of infectious and autoimmune diseases.
- Applications to different assay platforms, such as a portable, commercially available hand-held luminometer or an automated, high-throughput device.
Competitive Advantages
- Highly efficient, rapid, and easy to perform.
- Low background signals.
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