Technology ID

Focused Electrostatic Collection of Aerosol Particles for Chemical Analysis by Spectroscopic Techniques

Lead Inventor
Kulkarni, Pramod (CDC)
Diwakar, Prasson (CDC)
Software / Apps
Research Materials
Occupational Safety and Health
Non-Medical Devices
Medical Devices
Consumer Products
Therapeutic Areas
Infectious Disease
Development Stages
Pre-Clinical (in vitro)
Development Status
  • In situ data available (on-site)
  • Prototype
Research Products
Research Equipment
Lead IC
This CDC-developed technology is an aerosol preconcentration unit (APU) designed for use with spectroscopic detection techniques, including emission, Raman, or infrared spectroscopies. Most existing pulsed microplasma techniques, such as laser-induced breakdown, for aerosols rely mainly on filter-based collection and suffer from poor accuracy, precision, and detection limits and require long sample collection times. The APU is designed to address these drawbacks by pre-concentrating the aerosol particles on a tip of a microelectrode (a few hundreds of micrometers in diameter) to allow near-real time measurements with superior accuracy and precision. The APU is designed to be small, low-pressure drop unit for its use in a battery-operated, hand-portable instrumentation.

The design significantly improves accuracy and precision of measurements relative to existing methods. The APU can be integrated with a microplasma source (such as a laser-induced plasma) and the optical spectrometer to obtain elemental composition of aerosol particles. The unique features of this invention allow: i) semi-continuous or near-real-time measurement of elemental composition of aerosol particles, ii) measurement with high accuracy, precision, and repeatability, iii) collection of particles using electrostatic principles, iv) higher flow rates with smaller pumps because of a very low pressure drop, v) reliable calibration of the system, vi) easy miniaturization for portable instruments, and vii) lower detection limits, as needed, by increasing the particle collection time and/or sampling flow rate.
Commercial Applications
  • Personal exposure measurements of metals
  • Air pollution studies
  • Elemental quantification in near real-time
  • Hazardous materials exposure determinations and identification
  • Biodefense, chemical-defense applications
  • Environmental and occupational epidemiology
  • Evaluation of engineering controls
Competitive Advantages
  • This APU allows accurate, near-real-time measurement of the elemental composition of aerosol particles in industrial and ambient atmospheres
  • Can be readily miniaturized and integrated into existing portable plasma, Raman, or IR spectroscopy instruments to allow on-site, semi-continuous measurement of aerosol particles
  • Provides lower detection limits compared to earlier technology, as needed, by increasing the particle collection time and/or sampling flow rate
Licensing Contact:
Mitzelfelt, Jeremiah