Technology ID
TAB-2743

Molecular Detection and Viral-Load Quantification for HIV-1 Groups M, N and O, and Simian Immunodeficiency Virus-cpz (SIVcpz)

E-Numbers
E-271-2013-0
Lead Inventor
Lal, Renu (CDC)
Co-Inventors
Pieniazek, Danuta (CDC)
Applications
Therapeutics
Research Materials
Occupational Safety and Health
Diagnostics
Consumer Products
Therapeutic Areas
Ophthalmology
Oncology
Infectious Disease
Endocrinology
Dental
Cardiology
Development Stages
Pre-Clinical (in vitro)
Development Status
  • In vitro data available
  • In situ data available (on-site)
Lead IC
CDC
ICs
CDC
This invention provides materials, methods, and assays for detecting HIV-1 groups M and O and optionally HIV-1 group N and simian immunodeficiency virus-cpz (SIV-cpz). Specific nucleic acid primers for hybridization, amplification, and detection of HIV-1 are also provided for. The nucleic acid amplification assays can detect small concentrations of HIV-1 and are also useful for quantitative examinations of viral load concentrations within biological samples.
Commercial Applications
  • Blood and plasma donation screening
  • Diagnostic detection of HIV-1
  • Public health programs
  • Monitoring HIV treatment and disease inhibition/progression
Competitive Advantages
  • Broad-use, generic viral detection for groups M, N and O HIV-1, and also SIVcpz
  • Requires minute quantities of virus for use, making this assay ideal for confirmation of early-stage infection
  • Sensitive and highly specific
  • Easily formulated for kits
  • Established efficacy in patient samples
Licensing Contact:
Mitzelfelt, Jeremiah
jeremiah.mitzelfelt@nih.gov