Technology ID

Capillary Viscometer for Measuring Viscosity of Macromolecular Solutions of Biological Relevance

Lead Inventor
Minton, Allen (NIDDK)
Grupi, Asaf (NIDDK)
Research Materials
Non-Medical Devices
Medical Devices
Development Stages
Pre-Clinical (in vitro)
Development Status
  • Prototype
  • In vitro data available
A capillary-based device and system for measuring the rheological properties of solutions of synthetic and biological polymers. The device automatically serially dilutes and varies the flow rate of a sample, permitting measurement of solution viscosity across wide ranges of concentration and shear rate without changing samples. The device can rapidly and accurately assay solute stability, solute-solvent and solute-solute interactions in solutions of proteins and other macromolecules of biotechnological and pharmaceutical interest, as well as solution injectability.
Commercial Applications
  • Rapid characterization of composition-dependent rheological properties of candidate biopharmaceuticals and industrial polymers.
Competitive Advantages
  • Automatic variation of solute concentration
  • Automatic variation of shear rate
  • Direct measurement of solution injectability
Licensing Contact:
Knezevic, Vladimir
Phone: (240) 856-0274