- In vitro data available
A capillary-based device and system for measuring the rheological properties of solutions of synthetic and biological polymers. The device automatically serially dilutes and varies the flow rate of a sample, permitting measurement of solution viscosity across wide ranges of concentration and shear rate without changing samples. The device can rapidly and accurately assay solute stability, solute-solvent and solute-solute interactions in solutions of proteins and other macromolecules of biotechnological and pharmaceutical interest, as well as solution injectability.
- Rapid characterization of composition-dependent rheological properties of candidate biopharmaceuticals and industrial polymers.
- Automatic variation of solute concentration
- Automatic variation of shear rate
- Direct measurement of solution injectability