Technology ID
TAB-2476
Capillary Viscometer for Measuring Viscosity of Macromolecular Solutions of Biological Relevance
E-Numbers
E-231-2012-0
Lead Inventor
Minton, Allen (NIDDK)
Co-Inventors
Grupi, Asaf (NIDDK)
Applications
Research Materials
Non-Medical Devices
Medical Devices
Development Stages
Pre-Clinical (in vitro)
Development Status
- Prototype
- In vitro data available
Lead IC
NIDDK
ICs
NIDDK
A capillary-based device and system for measuring the rheological properties of solutions of synthetic and biological polymers. The device automatically serially dilutes and varies the flow rate of a sample, permitting measurement of solution viscosity across wide ranges of concentration and shear rate without changing samples. The device can rapidly and accurately assay solute stability, solute-solvent and solute-solute interactions in solutions of proteins and other macromolecules of biotechnological and pharmaceutical interest, as well as solution injectability.
Commercial Applications
- Rapid characterization of composition-dependent rheological properties of candidate biopharmaceuticals and industrial polymers.
Competitive Advantages
- Automatic variation of solute concentration
- Automatic variation of shear rate
- Direct measurement of solution injectability
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