Technology ID
TAB-2475

Image Analysis Software for Quantitative Evaluation of Striation Patterns and their Defects in Skeletal Muscles

E-Numbers
E-264-2012-0
Lead Inventor
Liu, Wenhua (NIAMS)
Co-Inventors
Ralston, Evelyn (NIAMS)
Development Status
Prototype
Lead IC
NIAMS
ICs
NIAMS
Available for licensing is software written in MatLab for evaluating striation patters in images of skeletal muscle fibers for better sensitivity in the quantitation of skeletal muscle disorders. Skeletal muscles have a regular, periodic organization (the periodicity of the sarcomeres), which is not only structural but also functional. Muscle pathologies create disorder in the normally periodic myofibrils. Objective grading of muscle morphology is necessary to assess muscle health, compare biopsies, and evaluate treatments and the evolution of disease.
Commercial Applications
Drug development for muscular disorders.

Competitive Advantages
Automated analysis of sarcomere dysplasia for objective grading of muscle morphology.

Request More Info

Licensing Contact:
Shmilovich, Michael
shmilovm@nih.gov

Publications

  • Plotnikov SV, et al.
  • Friedrich O, et al.
  • Llewellyn ME, et al.
  • This record was updated as part of a batch update by the OTT team. The Owner of this record was updated from ‘Admin’ to the Licensing Contact listed on the record on 7/25/2024. If you have any questions or concerns, please reach out to ETT Support.

Collaborations

  • Licensing
  • Collaboration

Collaboration Description

  • The Light Imaging Section of NIAMS, NIH, is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate or commercialize software for image analysis of cells and tissues and skeletal muscle. For collaboration opportunities, please contact Wenhua Liu at liuw5@mail.nih.gov or 301-451-4815.
Date Published