Technology ID
TAB-1222

Assay for the Detection of a Variety of Tumors in Biological Specimens

E-Numbers
E-173-1998-0
Co-Inventors
Fisher, Larry
Fedarko, Neal
Young, Marian
Applications
Diagnostics
Therapeutic Areas
Oncology
Lead IC
NIDCR
The inventors have developed methods and reagents for the detection of bone sialoprotein (BSP) in biological samples. The technology relates to the disruption of a serum complex that masks the majority of BSP from established detection systems. Furthermore, there is evidence that there may be a more acidic form of BSP secreted not by normal bone, but only by tumors. Detection of BSP in serum may be a good marker of various bone diseases and a variety of cancers including breast, prostate, lung, and thyroid.
Licensing Contact:
Knezevic, Vladimir
vlado.knezevic@nih.gov
Phone: (240) 856-0274