Novel Methods for Reducing Inflammation and Treating Diseases such as Parkinson's and Alzheimer's Disease
- In vitro data available
- In vivo data available (animal)
This invention describes small-peptide and non-peptide molecules that inhibit microglia activation and prevent neuronal degeneration with a bi-modal dose response curve. The non-peptide compounds have also been shown to prevent dopamine neuronal degeneration in animal models. This invention provides compositions and methods for inhibiting inflammatory mechanisms and treating inflammation-related condition by administering ultra-low (femto-molar) doses of at least one compound of the invention. These compounds include morphinans, opioid peptides, and the tripeptide GGF.
- Therapeutic treatment of Parkinson, Alzheimers and other degenerative CNS disorders.
- These compounds are active at ultra-low concentrations.
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