Technology ID
TAB-5141
Electrochemical Impedance Spectroscopy (EIS) for Non-Destructive Assessment of Epithelial Integrity
E-Numbers
E-203-2023-0
Lead Inventor
Maminishkis, Arvydas
Lead IC
NEI
Co-Inventors
Bharti, Kapil
Forest, Craig
Lewallen, Colby
ICs
NEI
Applications
Research Materials
Medical Devices
Diagnostics
Therapeutic Areas
Oncology
Infectious Disease
Development Stages
Prototype
This technology includes a novel apparatus and method that utilizes Electrochemical Impedance Spectroscopy (EIS) to assess the integrity of epithelial cell membranes non-destructively. By applying frequency-modulated voltage signals and facilitating fluid exchange on both sides of the epithelial tissue, this technology allows researchers to characterize membrane-specific responses with unprecedented accuracy. This advancement opens new avenues for drug discovery and evaluation of stem cell therapies, making it a vital tool for both academic and commercial research.
Potential Commercial Applications
- Assessment of drug effects on epithelial cells in pharmaceutical research.
- Standardized evaluation of stem cell therapies targeting epithelial tissues.
- Research into epithelial physiology and pathology in various medical fields.
Competitive Advantages
- Non-invasive technique that preserves tissue integrity, allowing for repeated measurements.
- High-throughput capability enables faster drug discovery and evaluation processes.
- Reduces reliance on traditional invasive methods, making it accessible to a broader range of researchers.
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