Technology ID
TAB-490
Infectious cDNA Clone of GB Virus B and Uses Thereof
E-Numbers
E-173-1999-0
Lead IC
NIAID
Co-Inventors
Bukh, Jens
Yanagi, Masayuki
Purcell, Robert
Emerson, Suzanne
ICs
NIAID
Applications
Vaccines
Research Materials
Therapeutic Areas
Infectious Disease
The current invention provides nucleic acid sequences comprising the genomes of infectious GB virus B, the most closely related member of the Flaviviridae to hepatitis C virus (HCV). It also covers chimeric GBVB-HCV sequences and polypeptides for use in the development of vaccines and diagnostic assays for HCV and the development of screening assays for the identification of antiviral agents for HCV. Additional information can be found in Bukh et al. (1999), Virology 262, 470-478.
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