Technology ID
TAB-393
Method Of Identifying Inhibitors Of The Jak-STAT Signal Transduction Pathway
E-Numbers
E-176-1995-0
Lead IC
NHLBI
Co-Inventors
Leonard, Warren
ICs
NHLBI
Applications
Therapeutics
Research Materials
Diagnostics
The invention provides identification methods for agents which inhibit the Jak-STAT signaling transduction pathway. Drugs identified by these methods are candidates for the treatment of proliferative disorders dependent on the Jak-STAT pathway, including those caused by HTLV-1. In addition, such agents may be potent immunosuppressive drugs with potential applications not only for organ transplantation but also for treatment of autoimmune diseases.
Licensing Contact:
Shmilovich, Michael<br><a href="mailto:shmilovm@nih.gov?subject=Web Inquiry on [TAB-393] Method Of Identifying Inhibitors Of The Jak-STAT Signal Transduction Pathway&body=Please send me information about technology [TAB-393] Method Of Identifying Inhibitors Of The Jak-STAT Signal Transduction Pathway.">shmilovm@nih.gov</a><br>