FY-2024 Top 20 Commercially Successful Inventions

photo: syringe, ampoules
VACCINES & THERAPEUTICS
Rank   

1

SARS Cov-2 VaccinesGraham, et al.

NIAID

2

Prefusion RSV F Proteins for Vaccines    McLeallan, et al.

NIAID

3

Adoptive Immunotherapy with Enhanced TIL CellsGos, et al.

NCI

4Nutritional Supplement to Treat Macular DegenerationFerris, et al.

NEI

5

Streptococcus Pneumoniae VaccinesBeall, et al.

CDC

6

Intranasal Administration of Ketamine to Treat DepressionZarate, et al.       

NIMH

7

Preconditioning Patients for Adoptive T Cell TherapyBot, et al.

NCI

8CAR T-cell Therapy for Multiple MyelomaKochenderfer, et al.

NCI

10

Novel CRISPR Enzymes and Systems    Koonin, et al.    

NLM

11

Pox Virus Based Veterinary Vaccines     Moss, et al.

NIAID

15

Anti-Coronavirus Antibodies    Mascola, et al.    

NIAID

17

Chimeric Antigen Receptor Targeting B-CellsKochenderfer, et al.

NCI

18

AAV5 Gene Therapy for Hemophilia    Kotin, et al.

NHLBI

19

MUC-1 Tumor AntigenSchlom, et al.

NCI

20

Monoclonal Antibodies Against CD22Dimitrov, et al.

NCI

  
photo: human puzzle with stethoscope
DIAGNOSTICS
Rank   
9HIV-1 Diagnostic Test KitsGallo, et al.NCI
12DNA Probe for Breast Cancer Diagnosis (HER-2)King, et al.NCI
    
abstract illustration: instrumentation
INSTRUMENTATION & DEVICES
Rank   
16Transcranial Magnetic Stimulation SystemZangen, et al.NIDA, NINDS
    
photo: laboratory glassware
RESEARCH MATERIALS & SERVICES
Rank   

13

NIH OVCAR Cell LinesHamilton, et al.

NCI

14Cell Lines Established from Certain Human TumorsOie, et al.

NCI