FY-2019 Top 20 Commercially Successful Inventions

    (based on royalties on product sales)

photo: syringe, ampoules
VACCINES & THERAPEUTICS
Rank   
1Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1Erickson, et al.NCI
2Nutritional Supplement to Treat Macular DegenerationFerris, et al.NEI
3Proteosome Inhibitor for Treatment of Multiple MyelomaGupta, et al.NCI
4HPV Vaccines Based Upon Recombinant Papillomavirus Capsid ProteinsLowy et al.NCI
6Pox Virus Based Veterinary VaccinesMoss, et al.NIAID
7Ulipristal Acetate Treatment of Uterine Fibroids Nieman, et al.NICHD
9Daclizumab Treatment of Multiple SclerosisBielekova, et al.NINDS
10Palifermin for Treatment of Oral MucositisRubin, et al.NCI
16Dengue Virus VaccineLai, et al.NCI
15Multivalent Human-Bovine Rotavirus VaccineKapikian, et al.NIAID
19Japanese Encephalitis Virus VaccineLai, et al.NIAID
    
photo: human puzzle with stethoscope
DIAGNOSTICS
Rank   
5HIV-1 Diagnostic Test KitsGallo, et al.NCI
11HIV-1 Genotyping AssaysMedabalimi, et al.NCI
13DNA Probe for Breast Cancer Diagnosis (HER-2)King, et al.NCI
18Norwalk-like Virus ELISA AssayGreen, et al.NIAID
    
abstract illustration: instrumentation
INSTRUMENTATION & DEVICES
Rank   
20Transcranial Magnetic Stimulation SystemZangen, et al.NIDA
    
photo: laboratory glassware
RESEARCH MATERIALS
Rank   
8Digital PCRSilver, et al.NIAID
12Cell Lines Established from Certain Human TumorsOie, et al.NCI
14Murine Colon 38 Cell LineHollingshead, et al.NCI
17Ovarian Tumor AntigenHamilton, et al.NCI