FY-2014 Top 20 Commercially Successful Inventions

(based on royalties on product sales)

photo: syringe, ampoulesVACCINES & THERAPEUTICS
1Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1Erickson et al.NCI
2HPV Vaccines Based Upon Recombinant Papillomavirus Capsid ProteinsLowy et al.NCI
3Monoclonal Antibody for Treatment of RSVMurphy et al.NIAID
5Proteosome Inhibitor for Treatment of Multiple MyelomaGupta et al.NCI
7Nutritional Supplement to Treat Macular DegenerationFerris et al.NEI
8Vaccinia Virus Vector Used in Biologicals/VaccinesMoss et al.NCI
9Palifermin for Treatment of Oral MucositisRubin et al.NCI
12Conjugate Vaccine for Neisseria meningitidisGu et al.NIDCD
photo: human puzzle with stethoscopeDIAGNOSTICS
4Serological Detection of Antibodies and Nucleic Acid Detection of HIV-1Gallo et al.NCI
6DNA Probe for Breast Cancer Diagnosis (HER-2)King et al.NCI
10Breast and Ovarian Cancer Screening Test (BRAC-1)Wiseman et al.NIEHS
11Genoyping of HIV Protease GeneOroszlan et al.NCI
18Diagnostic for Norwalk-like VirusGreen et al.NIAID
abstract illustration: instrumentationINSTRUMENTATION & DEVICES
13Diffusion Tensor Magnetic Resonance ImagingBasser et al.NICHD
14Digital PCRSilver et al.NIAID
15Paclitaxel-Eluting Peripheral Stent SystemKinsella et al.NIA
17Laser Capture MicrodissectionLiotta et al.NCI
photo: laboratory glasswareRESEARCH MATERIALS
16Purified Transforming Growth Factor Beta (TGF-beta)Sporn et al.NCI
19Neutrophil Chemotactic Factor (IL-8)Matsushima et al.NCI
20Monoclonal Antibodies to CD25, CD69, CD90, and LY6A/EShevachNIAID