FY-2012 Top 20 Commercially Successful Inventions

(based on royalties on product sales)

photo: syringe, ampoulesVACCINES & THERAPEUTICS
1HPV Vaccines Based Upon Recombinant Papillomavirus Capsid ProteinsLowy et al.NCI
2Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1Erickson et al.NCI
3Monoclonal Antibody for Treatment of RSVMurphy et al.NIAID
5Proteosome Inhibitor for Treatment of Multiple MyelomaGupta et al.NCI
6Nutritional Supplement to Treat Macular DegenerationFerris et al.NEI
9Vaccinia Virus Vector Used in Biologicals/VaccinesMoss et al.NCI
10Paclitaxel as a Cancer TreatmentWilson et al.NIAID
12Palifermin for Treatment of Oral MucositisRubin et al.NCI
14Conjugate Vaccine for Neisseria meningitidisGu et al.NIDCD
photo: human puzzle with stethoscopeDIAGNOSTICS
4Serological Detection of Antibodies and Nucleic Acid Detection of HIV-1Gallo et al.NCI
7DNA Probe for Breast Cancer Diagnosis (HER-2)King et al.NCI
11Genoyping of HIV Protease GeneOroszlan et al.NCI
13Breast and Ovarian Cancer Screening Test (BRAC-1)Wiseman et al.NIEHS
19Diagnostic for Norwalk-like VirusGreen et al.NIAID
abstract illustration: instrumentationINSTRUMENTATION & DEVICES
8Diffusion Tensor Magnetic Resonance ImagingBasser et al.NICHD
15Paclitaxel-Eluting Peripheral Stent SystemKinsella et al.NIA
18Laser Capture MicrodissectionLiotta et al.NCI
photo: laboratory glasswareRESEARCH MATERIALS
16Purified Transforming Growth Factor Beta (TGF-beta)Sporn et al.NCI
17Neutrophil Chemotactic Factor (IL-8)Matsushima et al.NCI
20Monoclonal Antibody Reactive with Human Breast Cancer (TAG72)Schlom et al.NCI