FY-2010 Top 20 Commercially Successful Inventions

(based on royalties on product sales)

photo: syringe, ampoulesVACCINES & THERAPEUTICS
Rank   
1Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1Erickson et al.NCI
2HPV Vaccines Based Upon Recombinant Papillomavirus Capsid ProteinsLowy et al.NCI
3Monoclonal Antibody for Treatment of RSVMurphy et al.NIAID
4Proteosome Inhibitor for Treatment of Multiple MyelomaGupta et al.NCI
7Nutritional Supplement to Treat Macular DegenerationFerris et al.NEI
10Vaccinia Virus Vector Used in Biologicals/VaccinesMoss et al.NIAID
11AIDS Drug ddIMitsuya et al.NCI
12Paclitaxel as a Cancer TreatmentWilson et al.NCI
15Radioimmunotherapy for Non-Hodgkin's LymphomaGansow et al.NCI
18Modified Cyclodextrin for Enhanced Drug UptakePithaNIA
20Synthetic Thyrotropin as Adjuvant in Thyroid CancerWondisford et al.NIDDK
 
 
photo: human puzzle with stethoscopeDIAGNOSTICS
Rank   
6Serological Detection of Antibodies to HIV-1Gallo et al.NCI
8DNA Probe for Breast Cancer DiagnosisKing et al.NCI
9Genoyping of HIV Protease GeneOroszlan et al.NCI
16Diagnostic for Norwalk-like VirusGreen et al.NIAID
 
 
abstract illustration: instrumentationINSTRUMENTATION & DEVICES
Rank   
5Paclitaxel-Eluting Coronary Stent SystemKinsella et al.NIA
13Diffusion Tensor Magnetic Resonance ImagingBasser et al.NICHD
19Laser Capture MicrodissectionLiotta et al.NCI
 
 
photo: laboratory glasswareRESEARCH MATERIALS
Rank   
14Neutrophil Chemotactic Factor (IL-8)Matsushima et al.NCI
17Purified Transforming Growth Factor Beta (TGF-beta)Sporn et al.NCI