FY-2005 Top 20 Commercially Successful Inventions

(based on royalties on product sales)

photo: syringe, ampoulesVACCINES & THERAPEUTICS
Rank   
2Monoclonal Antibody for Treatment of RSVMurphy et al.NIAID
4AIDS Drug ddIMitsuya et al.NCI
5Paclitaxel as a Cancer TreatmentWilson et al.NCI
6Synthetic Thyrotropin as Adjuvant in Thyroid CancerWondisford et al.NIDDK
7Hepatitis A Vaccine (Strain HM-175)Daemer et al. / Funkhouser et al.NIAID
8Nutritional Supplement to Treat Macular DegenerationFerris et al.NEI
9Radioimmunotherapy for Non-Hodgkin's LymphomaGansow et al.NCI
10Proteosome Inhibitor for Treatment of Multiple MyelomaGupta et al.NCI
18AIDS Drug ddCMitsuya et al.NCI
 
 
photo: human puzzle with stethoscopeDIAGNOSTICS
Rank   
3Serological Detection of Antibodies to HIV-1Gallo et al. / Montagnier et al.NCI
12DNA Probe for Breast Cancer DiagnosisKing et al.NCI
13Genoyping of HIV Protease GeneOroszlan et al.NCI
15Serological Detection of Antibodies to HTLV-1Papas et al.NCI
 
 
abstract illustration: instrumentationINSTRUMENTATION & DEVICES
Rank   
1Paclitaxel-Eluting Coronary Stent SystemKinsella et al.NIA
11Enhanced Magnetic Resonance Imaging Through Magnetization TransferBalaban et al.NHLBI
14Laser Capture MicrodissectionLiotta et al.NCI
 
 
photo: laboratory glasswareRESEARCH MATERIALS
Rank   
16Reconstituted Basement MembraneKleinman et al.NIDCR
17Neutrophil Chemotactic Factor (Interleukin-8)Matsushima et al.NCI
19Transforming Growth Factor Beta (TGF-beta)Sporn et al.NCI
20Chemokine ReceptorsMurphy et al.NIAID