FY-2019 Top 20 Commercially Successful Inventions

(based on royalties on product sales)

photo: syringe, ampoules
VACCINES & THERAPEUTICS
Rank      
1 Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1 Erickson, et al. NCI
2 Nutritional Supplement to Treat Macular Degeneration Ferris, et al. NEI
3 Proteosome Inhibitor for Treatment of Multiple Myeloma Gupta, et al. NCI
4 HPV Vaccines Based Upon Recombinant Papillomavirus Capsid Proteins Lowy et al. NCI
6 Pox Virus Based Veterinary Vaccines Moss, et al. NIAID
7 Ulipristal Acetate Treatment of Uterine Fibroids  Nieman, et al. NICHD
9 Daclizumab Treatment of Multiple Sclerosis Bielekova, et al. NINDS
10 Palifermin for Treatment of Oral Mucositis Rubin, et al. NCI
16 Dengue Virus Vaccine Lai, et al. NCI
15 Multivalent Human-Bovine Rotavirus Vaccine Kapikian, et al. NIAID
19 Japanese Encephalitis Virus Vaccine Lai, et al. NIAID
       
photo: human puzzle with stethoscope
DIAGNOSTICS
Rank      
5 HIV-1 Diagnostic Test Kits Gallo, et al. NCI
11 HIV-1 Genotyping Assays Medabalimi, et al. NCI
13 DNA Probe for Breast Cancer Diagnosis (HER-2) King, et al. NCI
18 Norwalk-like Virus ELISA Assay Green, et al. NIAID
       
abstract illustration: instrumentation
INSTRUMENTATION & DEVICES
Rank      
20 Transcranial Magnetic Stimulation System Zangen, et al. NIDA
       
photo: laboratory glassware
RESEARCH MATERIALS
Rank      
8 Digital PCR Silver, et al. NIAID
12 Cell Lines Established from Certain Human Tumors Oie, et al. NCI
14 Murine Colon 38 Cell Line Hollingshead, et al. NCI
17 Ovarian Tumor Antigen Hamilton, et al. NCI