FY-2015 Top 20 Commercially Successful Inventions

(based on royalties on product sales)

photo: syringe, ampoules VACCINES & THERAPEUTICS
1 Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1 Erickson et al. NCI
2 HPV Vaccines Based Upon Recombinant Papillomavirus Capsid Proteins Lowy et al. NCI
5 Proteosome Inhibitor for Treatment of Multiple Myeloma Gupta et al. NCI
7 Nutritional Supplement to Treat Macular Degeneration Ferris et al. NEI
8 Vaccinia Virus Vector Used in Biologicals/Vaccines Moss et al. NIAID
9 Palifermin for Treatment of Oral Mucositis Rubin et al. NCI
17 Use of the Progesterone Receptor Modulator CDB-2914 for Treating Uterine Fibroids Nieman et al. NICHD
photo: human puzzle with stethoscope DIAGNOSTICS
4 Cloned DNA Sequences, Hybridizable with Genomic RNA of Lymphadenopathy-Associated Virus (LAV) Alizon et al. EM
6 DNA Probe for Breast Cancer Diagnosis (HER-2) King et al. NCI
12 Synthetic HIV Protease Gene and Method for Its Expression Medabalimi et al. NCI
16 Diagnostic for Norwalk-like Virus Green et al. NIAID
abstract illustration: instrumentation INSTRUMENTATION & DEVICES
10 Diffusion Tensor Magnetic Resonance Imaging Basser et al. NICHD
13 Paclitaxel-Eluting Peripheral Stent System Kinsella et al. NIA
15 Films Containing Energy-Absorbing Dyes for Microdissection Bonner et al. NIBIB
photo: laboratory glassware RESEARCH MATERIALS
3 Monoclonal Antibody for Treatment of RSV Murphy et al. NIAID
11 Digital PCR Silver et al. NIAID
14 Purified Transforming Growth Factor Beta (TGF-beta) Sporn et al. NCI
18 Cell line H12F3 Shevach NIAID
19 Stem Cell Factor-Responsive FϲεRI Bearing Human Mast Cell Line LAD2 Kirshenbaum et al. NIAID
20 Cloned, Hormone-Producing Choriocarcinoma Cell Lines Kohler NICHD