FY-2013 Top 20 Commercially Successful Inventions

(based on royalties on product sales)

photo: syringe, ampoulesVACCINES & THERAPEUTICS
Rank   
1Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1Erickson et al.NCI
2HPV Vaccines Based Upon Recombinant Papillomavirus Capsid ProteinsLowy et al.NCI
3Monoclonal Antibody for Treatment of RSVMurphy et al.NIAID
6Vaccinia Virus Vector Used in Biologicals/VaccinesMoss et al.NCI
9Conjugate Vaccine for Neisseria meningitidisGu et al.NIDCD
11Paclitaxel as a Cancer TreatmentWilson et al.NIAID
12Proteosome Inhibitor for Treatment of Multiple MyelomaGupta et al.NCI
 
 
photo: human puzzle with stethoscopeDIAGNOSTICS
Rank   
4Serological Detection of Antibodies and Nucleic Acid Detection of HIV-1Gallo et al.NCI
5DNA Probe for Breast Cancer Diagnosis (HER-2)King et al.NCI
8Breast and Ovarian Cancer Screening Test (BRAC-1)Wiseman et al.NIEHS
10Genoyping of HIV Protease GeneOroszlan et al.NCI
19Diagnostic for Norwalk-like VirusGreen et al.NIAID
 
 
abstract illustration: instrumentationINSTRUMENTATION & DEVICES
Rank   
7Diffusion Tensor Magnetic Resonance ImagingBasser et al.NICHD
13Paclitaxel-Eluting Peripheral Stent SystemKinsella et al.NIA
15Laser Capture MicrodissectionLiotta et al.NCI
18Digital PCRSilver et al.NIAID
 
 
photo: laboratory glasswareRESEARCH MATERIALS
Rank   
14Purified Transforming Growth Factor Beta (TGF-beta)Sporn et al.NCI
16Neutrophil Chemotactic Factor (IL-8)Matsushima et al.NCI
17Monoclonal Antibodies to CD25, CD69, CD90, and LY6A/EShevachNIAID
20Monoclonal Antibody Reactive with Human Breast Cancer (TAG72)Schlom et al.NCI