FY-2012 Top 20 Commercially Successful Inventions

(based on royalties on product sales)

photo: syringe, ampoules VACCINES & THERAPEUTICS
1 HPV Vaccines Based Upon Recombinant Papillomavirus Capsid Proteins Lowy et al. NCI
2 Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1 Erickson et al. NCI
3 Monoclonal Antibody for Treatment of RSV Murphy et al. NIAID
5 Proteosome Inhibitor for Treatment of Multiple Myeloma Gupta et al. NCI
6 Nutritional Supplement to Treat Macular Degeneration Ferris et al. NEI
9 Vaccinia Virus Vector Used in Biologicals/Vaccines Moss et al. NCI
10 Paclitaxel as a Cancer Treatment Wilson et al. NIAID
12 Palifermin for Treatment of Oral Mucositis Rubin et al. NCI
14 Conjugate Vaccine for Neisseria meningitidis Gu et al. NIDCD
photo: human puzzle with stethoscope DIAGNOSTICS
4 Serological Detection of Antibodies and Nucleic Acid Detection of HIV-1 Gallo et al. NCI
7 DNA Probe for Breast Cancer Diagnosis (HER-2) King et al. NCI
11 Genoyping of HIV Protease Gene Oroszlan et al. NCI
13 Breast and Ovarian Cancer Screening Test (BRAC-1) Wiseman et al. NIEHS
19 Diagnostic for Norwalk-like Virus Green et al. NIAID
abstract illustration: instrumentation INSTRUMENTATION & DEVICES
8 Diffusion Tensor Magnetic Resonance Imaging Basser et al. NICHD
15 Paclitaxel-Eluting Peripheral Stent System Kinsella et al. NIA
18 Laser Capture Microdissection Liotta et al. NCI
photo: laboratory glassware RESEARCH MATERIALS
16 Purified Transforming Growth Factor Beta (TGF-beta) Sporn et al. NCI
17 Neutrophil Chemotactic Factor (IL-8) Matsushima et al. NCI
20 Monoclonal Antibody Reactive with Human Breast Cancer (TAG72) Schlom et al. NCI