FY-2012 Top 20 Commercially Successful Inventions
(based on royalties on product sales)
 |
VACCINES & THERAPEUTICS | ||
| Rank | |||
| 1 | HPV Vaccines Based Upon Recombinant Papillomavirus Capsid Proteins | Lowy et al. | NCI |
| 2 | Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1 | Erickson et al. | NCI |
| 3 | Monoclonal Antibody for Treatment of RSV | Murphy et al. | NIAID |
| 5 | Proteosome Inhibitor for Treatment of Multiple Myeloma | Gupta et al. | NCI |
| 6 | Nutritional Supplement to Treat Macular Degeneration | Ferris et al. | NEI |
| 9 | Vaccinia Virus Vector Used in Biologicals/Vaccines | Moss et al. | NCI |
| 10 | Paclitaxel as a Cancer Treatment | Wilson et al. | NIAID |
| 12 | Palifermin for Treatment of Oral Mucositis | Rubin et al. | NCI |
| 14 | Conjugate Vaccine for Neisseria meningitidis | Gu et al. | NIDCD FDA |
 |
DIAGNOSTICS | ||
| Rank | |||
| 4 | Serological Detection of Antibodies and Nucleic Acid Detection of HIV-1 | Gallo et al. | NCI |
| 7 | DNA Probe for Breast Cancer Diagnosis (HER-2) | King et al. | NCI |
| 11 | Genoyping of HIV Protease Gene | Oroszlan et al. | NCI NIAID NIMH |
| 13 | Breast and Ovarian Cancer Screening Test (BRAC-1) | Wiseman et al. | NIEHS |
| 19 | Diagnostic for Norwalk-like Virus | Green et al. | NIAID |
 |
INSTRUMENTATION & DEVICES | ||
| Rank | |||
| 8 | Diffusion Tensor Magnetic Resonance Imaging | Basser et al. | NICHD NINDS |
| 15 | Paclitaxel-Eluting Peripheral Stent System | Kinsella et al. | NIA |
| 18 | Laser Capture Microdissection | Liotta et al. | NCI NIBIB |
 |
RESEARCH MATERIALS | ||
| Rank | |||
| 16 | Purified Transforming Growth Factor Beta (TGF-beta) | Sporn et al. | NCI |
| 17 | Neutrophil Chemotactic Factor (IL-8) | Matsushima et al. | NCI |
| 20 | Monoclonal Antibody Reactive with Human Breast Cancer (TAG72) | Schlom et al. | NCI |