FY-2011 Top 20 Commercially Successful Inventions

(based on royalties on product sales)

photo: syringe, ampoules VACCINES & THERAPEUTICS
1 Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1 Erickson et al. NCI
2 HPV Vaccines Based Upon Recombinant Papillomavirus Capsid Proteins Lowy et al. NCI
3 Monoclonal Antibody for Treatment of RSV Murphy et al. NIAID
4 Proteosome Inhibitor for Treatment of Multiple Myeloma Gupta et al. NCI
6 Nutritional Supplement to Treat Macular Degeneration Ferris et al. NEI
9 Paclitaxel as a Cancer Treatment Wilson et al. NCI
11 Vaccinia Virus Vector Used in Biologicals/Vaccines Moss et al. NIAID
12 AIDS Drug ddI Mitsuya et al. NCI
14 Synthetic Thyrotropin as Adjuvant in Thyroid Cancer Wondisford et al. NIDDK
15 Palifermin for Treatment of Oral Mucositis Rubin et al. NCI
photo: human puzzle with stethoscope DIAGNOSTICS
5 Serological Detection of Antibodies and Nucleic Acid Detection of HIV-1 Gallo et al. NCI
8 DNA Probe for Breast Cancer Diagnosis King et al. NCI
10 Genoyping of HIV Protease Gene Oroszlan et al. NCI
13 Breast and Ovarian Cancer Screening Test (BRAC-1) Wiseman et al. NIEHS
19 Diagnostic for Norwalk-like Virus Green et al. NIAID
abstract illustration: instrumentation INSTRUMENTATION & DEVICES
7 Diffusion Tensor Magnetic Resonance Imaging Basser et al. NICHD
18 Digital PCR Method and Assembly Silver et al. NIAID
20 Laser Capture Microdissection Liotta et al. NCI
photo: laboratory glassware RESEARCH MATERIALS
16 Neutrophil Chemotactic Factor (IL-8) Matsushima et al. NCI
17 Purified Transforming Growth Factor Beta (TGF-beta) Sporn et al. NCI