FY-2010 Top 20 Commercially Successful Inventions

(based on royalties on product sales)

photo: syringe, ampoules VACCINES & THERAPEUTICS
1 Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1 Erickson et al. NCI
2 HPV Vaccines Based Upon Recombinant Papillomavirus Capsid Proteins Lowy et al. NCI
3 Monoclonal Antibody for Treatment of RSV Murphy et al. NIAID
4 Proteosome Inhibitor for Treatment of Multiple Myeloma Gupta et al. NCI
7 Nutritional Supplement to Treat Macular Degeneration Ferris et al. NEI
10 Vaccinia Virus Vector Used in Biologicals/Vaccines Moss et al. NIAID
11 AIDS Drug ddI Mitsuya et al. NCI
12 Paclitaxel as a Cancer Treatment Wilson et al. NCI
15 Radioimmunotherapy for Non-Hodgkin's Lymphoma Gansow et al. NCI
18 Modified Cyclodextrin for Enhanced Drug Uptake Pitha NIA
20 Synthetic Thyrotropin as Adjuvant in Thyroid Cancer Wondisford et al. NIDDK
photo: human puzzle with stethoscope DIAGNOSTICS
6 Serological Detection of Antibodies to HIV-1 Gallo et al. NCI
8 DNA Probe for Breast Cancer Diagnosis King et al. NCI
9 Genoyping of HIV Protease Gene Oroszlan et al. NCI
16 Diagnostic for Norwalk-like Virus Green et al. NIAID
abstract illustration: instrumentation INSTRUMENTATION & DEVICES
5 Paclitaxel-Eluting Coronary Stent System Kinsella et al. NIA
13 Diffusion Tensor Magnetic Resonance Imaging Basser et al. NICHD
19 Laser Capture Microdissection Liotta et al. NCI
photo: laboratory glassware RESEARCH MATERIALS
14 Neutrophil Chemotactic Factor (IL-8) Matsushima et al. NCI
17 Purified Transforming Growth Factor Beta (TGF-beta) Sporn et al. NCI