FY-2010 Top 20 Commercially Successful Inventions
(based on royalties on product sales)
 | VACCINES & THERAPEUTICS | ||
| Rank | |||
| 1 | Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1 | Erickson et al. | NCI |
| 2 | HPV Vaccines Based Upon Recombinant Papillomavirus Capsid Proteins | Lowy et al. | NCI |
| 3 | Monoclonal Antibody for Treatment of RSV | Murphy et al. | NIAID |
| 4 | Proteosome Inhibitor for Treatment of Multiple Myeloma | Gupta et al. | NCI |
| 7 | Nutritional Supplement to Treat Macular Degeneration | Ferris et al. | NEI |
| 10 | Vaccinia Virus Vector Used in Biologicals/Vaccines | Moss et al. | NIAID |
| 11 | AIDS Drug ddI | Mitsuya et al. | NCI |
| 12 | Paclitaxel as a Cancer Treatment | Wilson et al. | NCI |
| 15 | Radioimmunotherapy for Non-Hodgkin's Lymphoma | Gansow et al. | NCI |
| 18 | Modified Cyclodextrin for Enhanced Drug Uptake | Pitha | NIA |
| 20 | Synthetic Thyrotropin as Adjuvant in Thyroid Cancer | Wondisford et al. | NIDDK |
 | DIAGNOSTICS | ||
| Rank | |||
| 6 | Serological Detection of Antibodies to HIV-1 | Gallo et al. | NCI |
| 8 | DNA Probe for Breast Cancer Diagnosis | King et al. | NCI |
| 9 | Genoyping of HIV Protease Gene | Oroszlan et al. | NCI |
| 16 | Diagnostic for Norwalk-like Virus | Green et al. | NIAID |
 | INSTRUMENTATION & DEVICES | ||
| Rank | |||
| 5 | Paclitaxel-Eluting Coronary Stent System | Kinsella et al. | NIA |
| 13 | Diffusion Tensor Magnetic Resonance Imaging | Basser et al. | NICHD |
| 19 | Laser Capture Microdissection | Liotta et al. | NCI |
 | RESEARCH MATERIALS | ||
| Rank | |||
| 14 | Neutrophil Chemotactic Factor (IL-8) | Matsushima et al. | NCI |
| 17 | Purified Transforming Growth Factor Beta (TGF-beta) | Sporn et al. | NCI |