FY-2008 Top 20 Commercially Successful Inventions

(based on royalties on product sales)

photo: syringe, ampoules VACCINES & THERAPEUTICS
2 HPV Vaccines Based Upon Recombinant Papillomavirus Capsid Proteins Lowy et al. NCI
3 Monoclonal Antibody for Treatment of RSV Murphy et al. NIAID
4 Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1 Erickson et al. NCI
5 Proteosome Inhibitor for Treatment of Multiple Myeloma Gupta et al. NCI
7 AIDS Drug ddI Mitsuya et al. NCI
8 Synthetic Thyrotropin as Adjuvant in Thyroid Cancer Wondisford et al. NIDDK
10 Paclitaxel as a Cancer Treatment Wilson et al. NCI
11 Nutritional Supplement to Treat Macular Degeneration Ferris et al. NEI
12 Hepatitis A Vaccine (Strain HM-175) Daemer et al. / Funkhouser et al. NIAID
14 Vaccinia Virus Vector Used in Veterinary Biologicals/Vaccines Moss et al. NIAID
17 Palifermin for Treatment of Oral Mucositis Rubin et al. NCI
photo: human puzzle with stethoscope DIAGNOSTICS
6 Serological Detection of Antibodies to HIV-1 Gallo et al. / Montagnier et al. NCI
9 DNA Probe for Breast Cancer Diagnosis King et al. NCI
15 Norwalk Virus - IVD Product Green et al. NIAID
18 Genoyping of HIV Protease Gene Oroszlan et al. NCI
20 Serological Detection of Antibodies to HTLV-1 Papas et al. NCI
abstract illustration: instrumentation INSTRUMENTATION & DEVICES
1 Paclitaxel-Eluting Coronary Stent System Kinsella et al. NIA
13 Diffusion Tensor Magnetic Resonance Imaging Basser et al. NICHD
16 Enhanced Magnetic Resonance Imaging Through Magnetization Transfer Balaban et al. NHLBI
photo: laboratory glassware RESEARCH MATERIALS
19 Purified Transforming Growth Factor Beta (TGF-beta) Sporn et al. NCI