Technology ID
TAB-2976

A Novel Rapid Point-of Care Diagnostic Method for Infectious and Autoimmune Diseases

E-Numbers
E-190-2015-0
Lead Inventor
Burbelo, Peter (NIDCR)
Applications
Non-Medical Devices
Medical Devices
Diagnostics
Therapeutic Areas
Infectious Disease
Immunology
Geriatrics
Endocrinology
Development Stages
Discovery
Development Status
  • Early-stage
  • In vitro data available
  • Prototype
Research Products
Research Equipment
Antibodies
Lead IC
NIDCR
ICs
NIDCR
Rapid point-of-care, antibody-based testing is not available for the diagnosis of autoimmune and most infectious diseases. For detecting autoantibodies associated with most autoimmune conditions, fluid-phase immunoprecipitation assays are required. However, these assays usually involve radioactivity and are not feasible for point-of-care applications. The subject invention describes methods of using neodymium magnet for diagnosis of infectious and autoimmune diseases including lupus, Sjögren's syndrome, type I diabetes, HIV and Lyme disease. The assay takes 3.5 minutes, is highly efficient, and has low background.
Commercial Applications
  • A rapid assay for point-of-care diagnosis of infectious and autoimmune diseases.
  • Applications to different assay platforms, such as a portable, commercially available hand-held luminometer or an automated, high-throughput device.
Competitive Advantages
  • Highly efficient, rapid, and easy to perform.
  • Low background signals.
Licensing Contact: