FY-2006 Top 20 Commercially Successful Inventions

(based on royalties on product sales)

photo: syringe, ampoules VACCINES & THERAPEUTICS
Rank      
2 Monoclonal Antibody for Treatment of RSV Murphy et al. NIAID
3 AIDS Drug ddI Mitsuya et al. NCI
4 Synthetic Thyrotropin as Adjuvant in Thyroid Cancer Wondisford et al. NIDDK
6 Paclitaxel as a Cancer Treatment Wilson et al. NCI
7 Hepatitis A Vaccine (Strain HM-175) Daemer et al. / Funkhouser et al. NIAID
8 Proteosome Inhibitor for Treatment of Multiple Myeloma Gupta et al. NCI
9 Nutritional Supplement to Treat Macular Degeneration Ferris et al. NEI
10 Radioimmunotherapy for Non-Hodgkin's Lymphoma Gansow et al. NCI
15 Palifermin for Treatment of Oral Mucositis Rubin et al. NCI
16 Cyclodextrin Formulations for Treatment of Thrush Pitha NIA
 
 
photo: human puzzle with stethoscope DIAGNOSTICS
Rank      
5 Serological Detection of Antibodies to HIV-1 Gallo et al. / Montagnier et al. NCI
11 DNA Probe for Breast Cancer Diagnosis King et al. NCI
13 Genoyping of HIV Protease Gene Oroszlan et al. NCI
17 Serological Detection of Antibodies to HTLV-1 Papas et al. NCI
20 Parvovirus Capsids for Detection of B19 Virus Antibodies Young et al. NHLBI
 
 
abstract illustration: instrumentation INSTRUMENTATION & DEVICES
Rank      
1 Paclitaxel-Eluting Coronary Stent System Kinsella et al. NIA
12 Enhanced Magnetic Resonance Imaging Through Magnetization Transfer Balaban et al. NHLBI
 
 
photo: laboratory glassware RESEARCH MATERIALS
Rank      
14 Neutrophil Chemotactic Factor (IL-8) Matsushima et al. NCI
18 Reconstituted Basement Membrane Kleinman et al. NIDCR
19 Transforming Growth Factor Beta (TGF-beta) Sporn et al. NCI