FY-2005 Top 20 Commercially Successful Inventions

(based on royalties on product sales)

photo: syringe, ampoules VACCINES & THERAPEUTICS
Rank      
2 Monoclonal Antibody for Treatment of RSV Murphy et al. NIAID
4 AIDS Drug ddI Mitsuya et al. NCI
5 Paclitaxel as a Cancer Treatment Wilson et al. NCI
6 Synthetic Thyrotropin as Adjuvant in Thyroid Cancer Wondisford et al. NIDDK
7 Hepatitis A Vaccine (Strain HM-175) Daemer et al. / Funkhouser et al. NIAID
8 Nutritional Supplement to Treat Macular Degeneration Ferris et al. NEI
9 Radioimmunotherapy for Non-Hodgkin's Lymphoma Gansow et al. NCI
10 Proteosome Inhibitor for Treatment of Multiple Myeloma Gupta et al. NCI
18 AIDS Drug ddC Mitsuya et al. NCI
 
 
photo: human puzzle with stethoscope DIAGNOSTICS
Rank      
3 Serological Detection of Antibodies to HIV-1 Gallo et al. / Montagnier et al. NCI
12 DNA Probe for Breast Cancer Diagnosis King et al. NCI
13 Genoyping of HIV Protease Gene Oroszlan et al. NCI
15 Serological Detection of Antibodies to HTLV-1 Papas et al. NCI
 
 
abstract illustration: instrumentation INSTRUMENTATION & DEVICES
Rank      
1 Paclitaxel-Eluting Coronary Stent System Kinsella et al. NIA
11 Enhanced Magnetic Resonance Imaging Through Magnetization Transfer Balaban et al. NHLBI
14 Laser Capture Microdissection Liotta et al. NCI
 
 
photo: laboratory glassware RESEARCH MATERIALS
Rank      
16 Reconstituted Basement Membrane Kleinman et al. NIDCR
17 Neutrophil Chemotactic Factor (Interleukin-8) Matsushima et al. NCI
19 Transforming Growth Factor Beta (TGF-beta) Sporn et al. NCI
20 Chemokine Receptors Murphy et al. NIAID