Technology ID
TAB-3083

Immortalized Organ of Corti Cell Line OC-k3

E-Numbers
E-012-2017-0
Lead Inventor
Canseco De Kalinec, Gilda (NIDCD)
Co-Inventors
Kalinec, Federico (NIDCD)
Applications
Research Materials
Therapeutic Areas
Ophthalmology
Oncology
Infectious Disease
Endocrinology
Dental
Cardiology
Lead IC
NIDCD
ICs
NIDCD
Available for nonexclusive licensing as a research material is a conditionally immortalized Organ of Corti cell line called OC-k3. Sensory cells from the auditory organ, the Organ of Corti, are terminally differentiated and cannot be cultured. Moreover, few of them can be isolated per cochlea and survive only few hours after isolation making impossible to use on them many biochemical and molecular biology techniques. OC-k3, expresses many markers of sensory cells and it has already been used as an in vitro model for a variety of studies.
Commercial Applications
  • Research
  • Hearing research
  • Susceptibility to ototoxic drugs
Licensing Contact:
Shmilovich, Michael
shmilovm@nih.gov