Automated Identification of Subjects at Risk of Multiple Sclerosis (AIMS)

This technology includes an automated and non-invasive assessment system called Automated Identification of subjects at risks of Multiple Sclerosis (AIMS) to assist clinicians in their diagnostic evaluation. A focus of AIMS is the ‘central vein sign’ (and other radiological findings). The methodology is composed of the following features:

1. Ultra-fast high-resolution susceptibility imaging of the brain using novel MRI technique called 3D segmented echo-planar-imaging
2. Novel MRI contrasts (e.g., FLAIR*, QSM) using advanced processing
3. Fully automated detection for brain lesions, central vein sign and lesion rims, using novel statistical/machine-learning techniques

AIMS will ultimately generate a report describing all the information obtained from the image analysis and will classify the patients as either a low risk or high risk for MS.