Technology Bundle ID

A Novel Rapid Point-of Care Diagnostic Method for Infectious and Autoimmune Diseases

Linked ID
Lead Inventors
Peter Burbelo (NIDCR)
Development Status
  • Early-stage
  • In vitro data available
  • Prototype
Therapeutic Areas
Infectious Disease
Rapid point-of-care, antibody-based testing is not available for the diagnosis of autoimmune and most infectious diseases. For detecting autoantibodies associated with most autoimmune conditions, fluid-phase immunoprecipitation assays are required. However, these assays usually involve radioactivity and are not feasible for point-of-care applications. The subject invention describes methods of using neodymium magnet for diagnosis of infectious and autoimmune diseases including lupus, Sjögren's syndrome, type I diabetes, HIV and Lyme disease. The assay takes 3.5 minutes, is highly efficient, and has low background.
Commercial Applications
  • A rapid assay for point-of-care diagnosis of infectious and autoimmune diseases.
  • Applications to different assay platforms, such as a portable, commercially available hand-held luminometer or an automated, high-throughput device.
Competitive Advantages
  • Highly efficient, rapid, and easy to perform.
  • Low background signals.

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